Medication info

GC Wellbeing Acetaminophen Injection

Prescription medicationInjections정맥
Ingredient · strength
Acetaminophen›1000mg / 100mL
Manufacturer / importer
(주)녹십자웰빙
Appearance
A clear, colorless to pale yellow solution in a plastic vial for injection
Packaging
100 milliliters/pack
Approval status
Active

MFDS item code 202000931 · Notified 2020.02.13

Summary

Main use
Short-term relief of moderate pain (post-surgical) and fever
Who receives it
Adults · Children
Adult administration
Adults weighing 50 kg or more Administer 1000 mg of acetaminophen, 4 times a day Dosing interval: at least every 4 hours Maximum daily dose: not to exceed 4 grams Adults weighing between 33 kg and 50 kg Administer approximately 15 mg/kg of acetaminophen per single dose Dosing interval: at least every 4 hours Maximum daily dose: 60 mg/kg or not to exceed 4 grams Severe kidney impairment patients (creatinine clearance
Child administration
Pediatric patients weighing 33 kg (approximately 11 years old) or more Administer about 15 mg/kg of acetaminophen per single dose Dosing interval: at least every 4 hours Maximum daily dose: 60 mg/kg or not to exceed 4 grams

Ingredients

Manufacturer
(주)녹십자웰빙

Efficacy & effects

Short-term relief of moderate pain (post-surgical) and fever

  • Moderate pain
  • post-surgical pain
  • fever
View approved original text

This medication is used for intravenous administration when symptoms such as pain or high fever are present and cannot be administered by other routes, or when rapid effects are required. It helps to treat moderate pain, particularly pain occurring after surgery, over a short duration. It is also used to alleviate fever in the short term. It is effective for managing pain and fever, aiding in the improvement of the patient's symptoms.

How it is given

Adult administration

Adults weighing 50 kg or more Administer 1000 mg of acetaminophen, 4 times a day Dosing interval: at least every 4 hours Maximum daily dose: not to exceed 4 grams Adults weighing between 33 kg and 50 kg Administer approximately 15 mg/kg of acetaminophen per single dose Dosing interval: at least every 4 hours Maximum daily dose: 60 mg/kg or not to exceed 4 grams Severe kidney impairment patients (creatinine clearance

Child administration

Pediatric patients weighing 33 kg (approximately 11 years old) or more Administer about 15 mg/kg of acetaminophen per single dose Dosing interval: at least every 4 hours Maximum daily dose: 60 mg/kg or not to exceed 4 grams

Precautions

This medication must be administered at the exact dosage, as confusion between milligrams and milliliters can lead to serious poisoning or death. Once oral medication can be taken, it is advisable to use appropriate analgesics as soon as possible. It is essential to check if other medications being taken contain acetaminophen to avoid overdose. Exceeding the recommended dosage can cause serious liver damage; therefore, patients with liver function issues or liver disease should only take this medication after consulting a physician. Individuals who frequently consume alcohol should consult a healthcare professional before taking this medication due to the risk of liver damage. If serious skin reactions such as rashes or allergic reactions occur during the use of this medication, ingestion must be stopped immediately and medical advice sought. Patients with hypersensitivity to acetaminophen or this medication, as well as those with peptic ulcers, severe blood disorders, liver, kidney, or heart diseases, should not take this medication. Patients taking aspirin, certain antidepressants, or barbiturates should also avoid this medication. Careful use is required for those with liver or kidney problems, bleeding tendencies, hypersensitivity, asthma, the elderly, pregnant or breastfeeding women, and consultations with specialists are necessary before use. This medication may rarely cause side effects such as blood disorders, liver dysfunction, neurological issues, skin rashes, and injection site reactions, and immediate reporting of any unusual symptoms is important. Interactions may occur when taken with other medications, so inform the physician or pharmacist of any medications being taken. Caution is particularly needed when co-administered with probenecid, salicylamide, isoniazid, carbamazepine, phenytoin, and oral anticoagulants. This medication does not affect driving or machine operation and should not be mixed with other medications. Children and the elderly should take minimal dosages and be monitored for adverse reactions, especially if experiencing high fever. During pregnancy, the use of this medication is limited, but it should be administered cautiously under a physician's judgment if necessary, and it can be used safely while breastfeeding. Patients with severely impaired kidney function should increase the dosing interval. In cases of overdose, symptoms such as nausea, vomiting, and abdominal pain may occur, and in severe cases, can lead to liver damage or coma, necessitating immediate hospital treatment. This medication should not be stored at temperatures above 30 degrees Celsius, and refrigeration or freezing should be avoided. Prior to use, ensure there are no abnormalities in the solution, and any remaining solution after a single use should be discarded.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), anaphylactic shock, shock, acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute renal failure, fulminant hepatitis, liver necrosis, liver failure, angioedema, anaphylaxis, liver abnormalities (jaundice), agranulocytosis, neutropenia, leukopenia, thrombocytopenia, Lyell syndrome, coma, liver toxicity, severe edema, or urination abnormalities

Mild side effects

Fatigue, hypotension, increased liver transaminase levels, neurological disorders, maculopapular rash, injection site reactions, morbilliform rash, similar to pemphigus reactions, pustular rash, nausea, vomiting, headache, constipation, phlegm, sensory abnormalities, dizziness, reduced hemoglobin, urination disorders, thrombocytopenia, tachycardia, nausea, erythema, flushing, itching, rash, hives, high anion gap metabolic acidosis (HAGMA)

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent air and moisture from entering, at a safe temperature between 1 to 30 degrees Celsius. Therefore, it is important to avoid direct sunlight and not to place it in excessively hot or cold locations to maintain efficacy and prevent deterioration.

Appearance and packaging

Appearance

A clear, colorless to pale yellow solution in a plastic vial for injection

Package unit

100 milliliters/pack

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.