Medication info

Alzakin Tablet 1 mg (Rasagiline Mesylate)

Prescription medicationTabletOralExpired
Ingredient · strength
Rasagiline Mesylate›1.56mg / 1 tablet
Manufacturer / importer
HanKook Pavis Pharmaceutical Co., Ltd.
Appearance
Flat round tablet with white or almost white edges
Packaging
30 tablets/PTP [10 tablets/PTP*3], 30 tablets/bottle
Approval status
Expired

MFDS item code 202000657 · Approved 2020.02.05

This product's status changed to Expired on 2025.02.05. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of idiopathic Parkinson's disease
Who takes it
Adults
Adult dose
This product is administered orally once daily to adults as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If well tolerated and an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This product may be taken with or without food.

Ingredients

Manufacturer
HanKook Pavis Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of idiopathic Parkinson's disease

  • Idiopathic Parkinson's disease
  • motor fluctuation symptoms
View approved original text

This medication is used in the treatment of idiopathic Parkinson's disease. Initially, it is used as monotherapy or as an adjunctive therapy with an agonist to alleviate symptoms. Subsequently, it is applied as an adjunctive therapy with levodopa to patients who exhibit end-of-dose fluctuations, which is the time when the effects of the medication diminish. This improves motor function and effectively controls symptoms in Parkinson's disease patients.

How to take

Adult dose

This product is administered orally once daily to adults as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If well tolerated and an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This product may be taken with or without food.

Precautions

This medication should not be used by patients who are allergic to any of the active ingredients or other components. Additionally, patients currently taking or who have recently stopped taking other MAO inhibitors or specific medications such as pethidine, tramadol, or dextromethorphan should not be administered this medication. Patients with moderate or severe liver dysfunction should not use this medication, and patients with mild liver impairment should use it with caution. Various side effects may occur during the use of this medication, commonly reported effects include headache, dizziness, nausea, dermatitis, and musculoskeletal pain. Rarely, serious adverse reactions such as malignant hyperthermia, acute renal failure, and hypertension may occur, so patients should consult a physician immediately if symptoms arise. This medication can cause drowsiness or sudden sleep, so caution is required when driving or operating dangerous machinery, and such activities should be avoided if these symptoms occur. Moreover, taking this medication along with certain medications or natural products can lead to severe interactions, so it is essential to consult with a physician or pharmacist. Caution is advised when using this medication during pregnancy or while breastfeeding, and safety and efficacy have not been established in children under 18 years of age. In case of overdose, severe side effects may occur, so the prescribed dosage should be strictly adhered to, and it should be stored in a cool place out of reach of children.

Side effects

  • Influenza
  • skin cancer
  • leukopenia
  • allergy
  • loss of appetite
  • depression
  • hallucinations
  • headache
  • cerebrovascular accident
  • conjunctivitis
Show 115 more
  • dizziness
  • angina
  • myocardial infarction
  • rhinitis
  • abdominal distension
  • dermatitis
  • vesicular rash
  • musculoskeletal pain
  • neck pain
  • arthritis
  • urinary urgency
  • fever
  • malaise
  • peripheral edema
  • falls
  • arthralgia
  • low back pain
  • cough
  • insomnia
  • upper respiratory tract infection
  • orthostatic hypotension
  • nausea
  • constipation
  • vomiting
  • dry mouth
  • diarrhea
  • abdominal pain
  • dyspepsia
  • hernia
  • infection
  • gingivitis
  • accidental injury
  • weight loss
  • tendinitis
  • movement disorders
  • drowsiness
  • sensory abnormalities
  • ataxia
  • muscle rigidity
  • myasthenia
  • decreased appetite
  • abnormal dreams
  • respiratory distress
  • rash
  • hyperhidrosis
  • petechiae
  • melanoma
  • disorientation
  • carpal tunnel syndrome
  • balance disorder
  • hypotension
  • pathological gambling
  • increased libido
  • hypersexuality
  • compulsive spending or purchasing
  • binge eating
  • compulsive eating
  • excessive drowsiness
  • acute renal failure
  • malignant hyperthermia
  • general weakness
  • pulmonary tuberculosis
  • semi-coma
  • gait disturbance
  • ocular motor seizures
  • facial paralysis
  • spinal stenosis
  • exacerbation of Parkinson's disease
  • subdural hematoma
  • pneumonia
  • vertebral fracture
  • rib fracture
  • tendon injury
  • pelvic fracture
  • leg fracture
  • upper limb fracture
  • low back pain
  • knee arthroplasty
  • herniated disc
  • hypoglycemia
  • weight loss
  • dysuria
  • palpitations
  • arrhythmia
  • heartburn
  • fatigue
  • delusion
  • sleep disorder
  • aggression
  • amnesia
  • memory impairment
  • lethargy
  • sleep talking
  • psychosexual disorder
  • skin tingling
  • tremor
  • freezing phenomenon
  • limb tremors
  • dyskinesia
  • leg cramps
  • polyuria
  • tremors
  • stuttering
  • speech impairment
  • vocal cord paralysis
  • language disorder
  • itching
  • urticaria
  • abscess
  • hair loss
  • contusion
  • abnormal sputum
  • increased sputum
  • cold
  • bronchitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. A storage temperature between 1 and 25 degrees Celsius in a cool place is appropriate. Proper storage will safely maintain the medication's efficacy.

Appearance and packaging

Appearance

Flat round tablet with white or almost white edges

Package unit

30 tablets/PTP [10 tablets/PTP*3], 30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

Related searches

Search tags

Suggested searches

This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.