Actorin Tablets 30 mg (Pioglitazone Hydrochloride)

Adult dose

This medication should be taken orally once a day, regardless of meals. For monotherapy, start with 15 mg once daily, and if the effect is insufficient, it may be increased to 30 mg once daily. For combination therapy, administer 15 mg once daily along with sulfonylureas, metformin, or insulin, with a maximum recommended dose of 30 mg once daily.

Child dose

There is no experience in children under 18 years, so administration is not recommended.

This medication is used for the treatment of type 2 diabetes and needs insulin to lower blood sugar effectively. During the course of this medication, symptoms of heart failure may occur, such as sudden weight gain, shortness of breath, and swelling of the legs; if these symptoms arise, inform your doctor immediately. Patients with heart failure or a history of heart failure should not use this medication, nor should patients with active bladder cancer or a history of bladder cancer, or patients with severe liver or kidney dysfunction. Women who are pregnant or may become pregnant should not take this medication, and premenopausal women may have a higher risk of pregnancy due to ovulation while on this medication, so appropriate contraception is necessary. The risk of hypoglycemia may increase when this medication is used with other diabetes medications; hence, symptoms of hypoglycemia and management strategies should be well understood and dosage adjustments may be needed for other medications. Regular liver function tests should be conducted during treatment, and if symptoms of liver dysfunction (fatigue, loss of appetite, pain in the upper right abdomen, jaundice, etc.) occur, consult a doctor immediately. Swelling or weight gain may occur, and these symptoms can improve upon discontinuation of the medication. Long-term use of this medication may increase the risk of fractures, so special attention to bone health is especially necessary for women. If visible blood in the urine or urination disorders occur during treatment, inform your doctor immediately as it may indicate the possibility of bladder cancer. This medication is taken once daily, and if a dose is missed, do not double the dose the next day. Safety and efficacy have not been established in children and adolescents under 18 years of age. Elderly patients need special attention, and those over 75 years old should use the medication with increased caution. This medication may interact with other drugs; therefore, inform your doctor or pharmacist of any other medications being taken.

Serious side effects

Congestive heart failure, heart failure symptoms (excessive weight gain, difficulty breathing, swelling), severe edema, severe allergic reactions (urticaria, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness), liver abnormalities (liver dysfunction, jaundice, fatigue, loss of appetite, discomfort in the upper right abdomen, dark urine), severe skin reaction (severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa), serious neurological symptoms

Mild side effects

• Headache
• sinusitis
• myalgia
• pharyngitis
• upper respiratory tract infections
• abdominal bloating
• weight gain
• hypoglycemia
• urinary tract infections
• low back pain

This medication is sensitive to light, so it should be stored in a container that does not allow light to enter. Additionally, avoid humid areas and store in a cool place between 15 and 30 degrees Celsius.

Appearance

White to grayish-white round tablets

Package unit

30 tablets/bottle, 300 tablets/bottle