Megapamo Tablet 20 mg (Famotidine)

Adult dosage

Oral administration: 20 mg once, twice a day (after breakfast, after dinner, or at bedtime) or 40 mg once a day (at bedtime). Injectable: Dissolve 20 mg in 20 mL of normal saline or dextrose solution and slowly administer by intravenous injection twice a day (every 12 hours) or infuse it with IV fluids. Pre-anesthetic medication: Dissolve 20 mg in 1-1.5 mL of injection water and administer intramuscularly 1 hour before induction of anesthesia.

This medication should not be used in patients with allergies to specific components or inherited lactose intolerance. It should be used with caution in patients with poor kidney or liver function, heart disease, a history of drug allergies, and in elderly patients. While rare, serious allergic reactions, blood abnormalities, severe skin disorders, liver dysfunction, muscle damage, cardiac arrhythmias, neurological issues, renal deterioration, and pulmonary diseases may occur during treatment, so any unusual symptoms should be promptly discussed with a physician. This medication dissolves in the mouth but is not absorbed in the mouth, so it should be swallowed with water or saliva. Regular blood tests and tests for liver and kidney function are recommended. Care should be taken due to possible interactions with other drugs, especially when taking specific antifungals or anticancer medications. Pregnant or breastfeeding women should carefully consider the risks and benefits before using this medication, and in the case of breastfeeding, discontinuation of breastfeeding is advisable. The safety for children has not been fully established, so caution is needed in its use. In particular, this medication can mask symptoms of gastric cancer, so it should only be used after confirming that it is not cancer. When taking this medication, it is advisable to use the minimum effective dose based on symptoms, and if there is no effect, to switch to another treatment. Elderly patients may have prolonged drug retention due to decreased renal function, necessitating a reduction in dosage or an increase in dosing interval.

Serious side effects

Shock, hypersensitivity (anaphylaxis, respiratory distress, generalized erythema, angioedema [facial swelling, laryngeal edema, etc.], urticaria), pancytopenia, agranulocytosis, aplastic anemia, hemolytic anemia, thrombocytopenia (general fatigue, lethargy, subcutaneous and mucosal bleeding, fever), Stevens-Johnson syndrome (mucocutaneous syndrome), Lyell's syndrome (toxic epidermal necrolysis), liver dysfunction, jaundice (elevated AST [GOT], ALT [GPT], jaundice), rhabdomyolysis.

Mild side effects

• Rash
• urticaria (erythema)
• facial swelling
• leukopenia
• eosinophilia
• constipation
• diarrhea
• dry mouth
• nausea
• vomiting

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, and it is important to keep the storage temperature between 1 to 30 degrees Celsius at room temperature. This will help maintain the medication's effectiveness.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 1000 tablets/bottle