Megaomezol Capsule 20mg (Omeprazole)

Adult dose

1) Gastric ulcer: Administer 20mg of omeprazole orally once daily. Most ulcers may heal within 4 weeks, although the healing period may vary in some patients. If the ulcer has not healed after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to other agents, administration of 40mg once daily generally results in healing within 8 weeks, although the healing period may vary in some patients. If the ulcer recurs, repeat treatment. 2) Short-term treatment of duodenal ulcer: Administer 20mg orally once daily. Most ulcers may heal within 2 weeks, although the healing period may vary in some patients. If the ulcer has not healed after the initial 2 weeks of treatment, continue treatment for an additional 2 weeks. In patients who have not responded to other agents, administration of 40mg once daily generally results in healing within 4 weeks, although the healing period may vary in some patients. If the ulcer recurs, repeat treatment. 3) Reflux esophagitis: Administer 20mg orally once daily. Most cases may heal within 4 weeks, although the healing period may vary in some patients. If the condition has not healed after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to other agents, administration of 40mg once daily generally results in healing within 8 weeks, although the healing period may vary in some patients. If the condition recurs, repeat treatment. 4) Zollinger-Ellison syndrome: The initial dose is 60mg orally once daily. Continue treatment, adjusting the dose appropriately for each individual. More than 90% of patients respond to doses of 20 - 120mg daily. If more than 80mg per day is administered, divide the daily dose into 2 doses. 5) Maintenance treatment for severe reflux esophagitis and refractory peptic ulcer: Administer 20mg orally once daily. If the condition recurs, the dose may be increased to 40mg once daily. 6) Combination therapy with antibiotics to prevent recurrence of duodenal ulcers infected with Helicobacter pylori: - Dual therapy: Administer this drug 20mg with amoxicillin 750 - 1000mg twice daily for 2 weeks. - Triple therapy: Administer this drug 40mg once daily or 20mg twice daily in combination with the following antibiotics. ① Administer clarithromycin 250mg and metronidazole 400mg twice daily for 1 week, or ② Administer amoxicillin 1g and clarithromycin 500mg twice daily for 1 week. If the treatment effect is insufficient, omeprazole monotherapy may be continued. 7) Treatment of symptoms of gastroesophageal reflux disease (GERD) (heartburn, regurgitation, etc.): Administer 20mg orally once daily. Treatment for 2-4 weeks generally results in healing. 8) Treatment of gastric or duodenal ulcers or erosions caused by nonsteroidal anti-inflammatory drugs (NSAIDs): Administer 20mg orally once daily. Most cases may heal within 4 weeks, although the healing period may vary in some patients. If the condition has not healed after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. 9) Maintenance prevention of gastric or duodenal ulcers or erosions and dyspeptic symptoms caused by NSAID administration in patients receiving long-term NSAID treatment who have a history of gastric or duodenal lesions: Administer 20mg orally once daily. * Swallow this drug whole with at least half a glass of water. Adjust the dose as appropriate according to age and symptoms.

This drug should not be used by patients who are allergic to its components. Caution is advised when administering this drug to patients with gastric ulcers suspected of being malignant as alleviation of symptoms may delay diagnosis of cancer. Combining this drug with atazanavir or medications containing rilpivirine may diminish treatment efficacy due to drug interactions, and should not be used together. It should not be administered to patients with a genetic inability to digest lactose, due to the lactose component present in this drug. Patients with impaired liver function may have increased plasma concentrations of this drug, so they should use a reduced dosage carefully, especially severe liver dysfunction patients should not exceed 20 mg per day. Elderly patients may be at higher risk for drug side effects, so caution should be exercised. This drug may cause neurological symptoms such as headache, dizziness, and drowsiness, and in rare cases may cause confusion or hallucinations. If liver enzyme levels rise or symptoms of jaundice occur, use should be immediately halted as liver function abnormalities can occur. This drug may affect the kidneys and rarely can lead to serious kidney disease such as nephritis, so if unusual symptoms arise, medical advice should be sought. Gastrointestinal side effects such as diarrhea, abdominal pain, nausea, and vomiting are common. Skin reactions such as rash, itching, or in severe cases, serious skin reactions like Stevens-Johnson syndrome may occur, and drug use should be discontinued immediately if these symptoms appear. Severe allergic reactions or anaphylactic shock may rarely occur and may require emergency measures if symptoms develop. A rare decrease in blood cell counts may occur, so testing is required if bleeding or infection symptoms arise. Long-term use may increase the risk of fractures and cause hypomagnesemia, so patients taking this drug for an extended period should have regular blood tests. This drug may interact with other medications, particularly anticoagulants like warfarin, diazepam, and cyclosporine, so consultation with a physician is essential when taking these drugs. Women who are pregnant or may become pregnant should use this drug cautiously as it may affect the fetus. Breastfeeding women should avoid or discontinue breastfeeding as this drug may be transmitted through breast milk. Safety in children has not been established, so caution is necessary when considering use. In case of overdose, symptoms such as vomiting, diarrhea, headache, and confusion may occur, and medical attention should be sought immediately if suspected. This drug must be kept out of reach of children, should not be transferred to other containers, and should be tightly closed and stored after use.

Headache, drowsiness, dizziness, insomnia, paresthesia, feeling faint, vertigo, confusion, agitation, aggression, hallucinations, depression, elevated liver enzymes, jaundice, hepatitis, liver failure, encephalopathy, interstitial nephritis, diarrhea, stool changes, constipation, nausea, vomiting, abdominal pain, abdominal distension, dry mouth, stomatitis, gastrointestinal candidiasis, flushing, rash, urticaria, itching, dermatitis, vesicular rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, photosensitivity, alopecia, angioedema, fever, bronchospasm, interstitial nephritis, anaphylactic shock, chest pain, tachycardia, bradycardia, palpitations, leukopenia, thrombocytopenia, agranulocytosis, pancytopenia, back pain, arthralgia, muscle weakness, myalgia, gynecomastia, cough, asthenia, fatigue, peripheral edema, increased sweating, blurred vision, visual disturbances, taste disorders, breast pain in women, breast lump, hyponatremia, erectile dysfunction, Clostridium difficile-associated diarrhea, hypomagnesemia, acute generalized pustular psoriasis, eosinophilia with systemic symptoms drug reaction, systemic lupus erythematosus, cutaneous lupus erythematosus, gastric polyp, hypocalcemia, hypokalemia

This drug should be stored in a tightly sealed container to prevent air or moisture ingress, ideally at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness over time.

Appearance

A hard capsule filled with light yellow enteric-coated granules, reddish-brown on the upper part and pink on the lower part.

Package unit

28 capsules/bottle