Medication info

Samsung Rasagiline Tablet 1.0 mg (Rasagiline Mesylate)

Prescription medicationTabletOralExpired
Ingredient · strength
Rasagiline Mesylate›1.56mg / 1 tablet
Manufacturer / importer
Samsung Pharmaceutical Co., Ltd.
Appearance
Flat round tablets with white or almost white edges
Packaging
30 tablets/Blister [(10 tablets/Blister x 3)]
Approval status
Expired

MFDS item code 202000578 · Approved 2020.02.04

This product's status changed to Expired on 2025.02.04. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of idiopathic Parkinson's disease
Who takes it
Adults
Adult dose
This medicine is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy with a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy with levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If well tolerated and an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Ingredients

Manufacturer
Samsung Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of idiopathic Parkinson's disease

  • Idiopathic Parkinson's disease
  • motor fluctuations
View approved original text

This medication is used as initial monotherapy in patients with idiopathic Parkinson's disease or as an adjunct therapy to dopamine agonists. It is also utilized as adjuvant therapy in patients experiencing end of dose fluctuations of motor symptoms. This effectively controls Parkinson's disease symptoms and improves the quality of life of patients.

How to take

Adult dose

This medicine is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy with a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy with levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If well tolerated and an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Precautions

This medication should not be used by individuals allergic to the active ingredient or other components. Do not administer this drug if you are currently taking or have stopped taking other MAO inhibitors within the last two weeks. It should not be used if you are currently taking or have stopped taking the analgesic pethidine within the last two weeks. Patients taking medications such as tramadol or dextromethorphan should also avoid using this medication due to the risk of serious side effects from interactions. Patients with moderate to severe liver impairment should not take this medication. This medication can cause various side effects, with common side effects including headache, dizziness, depression, hallucinations, dermatitis, and musculoskeletal pain. Particularly, Parkinson's patients should be cautious about the potential for movement disorders or hypotension. During treatment, obsessive behavior and impulse control disorders may occur, so both the patient and caregiver should closely monitor for these symptoms. Additionally, this medication can cause drowsiness or sudden sleep, necessitating caution when driving or operating machinery. Due to numerous interactions with other drugs, especially with MAO inhibitors, antidepressants, sympathomimetics, and certain analgesics, it is crucial to consult a healthcare professional before use. Pregnant or breastfeeding women need to be cautious when taking this medication, and it is advisable not to use it in children as safety has not been established. In case of overdose, serious side effects may occur, so adherence to the prescribed dosage is essential. If an overdose is suspected, seek medical attention immediately. Store this medication out of reach of children and maintain storage temperatures between 1 and 25 degrees Celsius. Avoid transferring it to different containers as this can compromise quality.

Side effects

  • Influenza
  • skin cancer
  • leukopenia
  • allergies
  • loss of appetite
  • depression
  • hallucinations
  • headache
  • cerebrovascular accident
  • conjunctivitis
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  • dizziness
  • angina
  • myocardial infarction
  • rhinitis
  • abdominal distension
  • dermatitis
  • vesicular rash
  • musculoskeletal pain
  • cervical pain
  • arthritis
  • urinary urgency
  • fever
  • fatigue
  • peripheral edema
  • falls
  • arthralgia
  • low back pain
  • cough
  • insomnia
  • upper respiratory infection
  • orthostatic hypotension
  • nausea
  • constipation
  • vomiting
  • dry mouth
  • diarrhea
  • abdominal pain
  • dyspepsia
  • hernia
  • infection
  • gingivitis
  • traumatic injury
  • weight loss
  • tendinitis
  • movement disorders
  • drowsiness
  • sensory abnormalities
  • ataxia
  • muscle tone abnormalities
  • myasthenia
  • loss of appetite
  • abnormal dreams
  • respiratory distress
  • rash
  • hyperhidrosis
  • petechiae
  • melanoma
  • confusion
  • carpal tunnel syndrome
  • balance disorders
  • hypotension
  • pathological gambling
  • increased libido
  • hypersexuality
  • compulsive buying or spending
  • binge eating
  • obsessive eating
  • excessive drowsiness
  • acute renal failure
  • malignant hyperthermia
  • generalized weakness
  • pulmonary tuberculosis
  • semi-coma
  • walking disorders
  • ocular movement seizures
  • facial paralysis
  • spinal canal stenosis
  • worsening of Parkinson's disease
  • subdural hematoma
  • pneumonia
  • spinal fracture
  • rib fracture
  • tendon injury
  • pelvic fracture
  • leg fracture
  • upper limb fracture
  • back pain
  • knee arthroplasty
  • intervertebral disc herniation
  • hypoglycemia
  • weight loss
  • dysuria
  • palpitations
  • arrhythmia
  • heartburn
  • fatigue
  • delusions
  • sleep disorders
  • aggression
  • amnesia
  • memory impairment
  • lethargy
  • sleep talking
  • psychosexual disorders
  • skin tingling
  • tremors
  • freezing phenomenon
  • limb tremors
  • myotonic dystrophy
  • leg cramps
  • polyuria
  • tremor
  • stuttering
  • speech disorder
  • vocal cord paralysis
  • language disorder
  • localized inflammation
  • itching
  • urticaria
  • abscess
  • hair loss
  • contusion
  • altered sputum
  • increased sputum
  • cold
  • bronchitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, and it is best kept in a cool place between 1 and 25 degrees Celsius. Avoid direct sunlight and high temperatures, and store it in a safe place to maintain the medication's effectiveness.

Appearance and packaging

Appearance

Flat round tablets with white or almost white edges

Package unit

30 tablets/Blister [(10 tablets/Blister x 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.