Medication info

Selparin Tablet 0.5 mg (Rasagiline Mesylate)

Prescription medicationTabletOralExpired
Ingredient · strength
Rasagiline Mesylate›0.78mg / 1 tablet
Manufacturer / importer
Seltrion Pharmaceutical Co., Ltd.
Appearance
Flat round tablet with corners, white or almost white
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Expired

MFDS item code 202000522 · Approved 2020.01.31

This product's status changed to Expired on 2025.01.31. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of idiopathic Parkinson’s disease
Who takes it
Adults
Adult dose
This medicine is administered orally once daily to adults as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy with a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy with levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If well tolerated and the clinical response is inadequate, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Ingredients

Manufacturer
Seltrion Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of idiopathic Parkinson’s disease

  • Idiopathic Parkinson's disease
  • motor fluctuations
View approved original text

This medication is used for the treatment of idiopathic Parkinson's disease. Initially, it can be used as monotherapy or combined as an adjunct therapy with dopamine agonists. It is also used as an adjunct therapy to levodopa treatment for patients who experience motor fluctuations known as 'end of dose fluctuations'. This helps effectively control symptoms and improves the quality of life of patients.

How to take

Adult dose

This medicine is administered orally once daily to adults as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy with a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy with levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If well tolerated and the clinical response is inadequate, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Precautions

This medication should not be taken by individuals who are allergic to its active substance or any other components. Additionally, it should not be used in patients who are currently taking or have stopped taking other MAO inhibitors for less than 2 weeks. It must not be administered to patients taking specific medications such as meperidine, tramadol, or dextromethorphan, or who have stopped taking these for less than 2 weeks. Patients with moderate to severe liver dysfunction should not take this medication, and caution is warranted for those with mild liver impairment. Various side effects such as cold symptoms, headache, dizziness, dermatitis, musculoskeletal pain, nausea, and insomnia may occur while taking this medication. In particular, Parkinson's disease patients may experience psychiatric symptoms such as hallucinations or confusion, necessitating caution. Serious adverse reactions can include increased blood pressure or hypotension, impulse control disorders, drowsiness, and sudden sleep attacks, and patients should immediately consult healthcare professionals if any symptoms arise. Dangerous interactions can occur when taken with other MAO inhibitors, certain analgesics, antidepressants, and sympathomimetics, so it is essential to inform a doctor or pharmacist. There is insufficient safety information regarding this medication for use during pregnancy or breastfeeding, so professional consultation is required before use. This medication is not recommended for children under 18 years of age due to insufficient safety and effectiveness data. This medication may affect driving or machine operation abilities, so patients should avoid hazardous activities if drowsiness or sleep attack symptoms occur while taking it. In case of overdose, severe hypertension or neurological abnormalities may occur; hence, dosages must strictly adhere to a doctor's direction, and immediate medical attention should be sought in case of overdose. This medication should be stored in a cool place out of reach of children and should not be transferred to another container.

Side effects

influenza

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is recommended to maintain storage temperatures between 1 and 25 degrees Celsius at room temperature.

Appearance and packaging

Appearance

Flat round tablet with corners, white or almost white

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.