Medication info
Youngil Lafutidine Tablet

Youngil Lafutidine Tablet

Prescription medicationTabletOral
Ingredient · strength
Lafutidine›10mg / 1 tablet
Manufacturer / importer
Youngil Pharmaceutical Co., Ltd.
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 202000494 · Approved 2020.01.30 · Insurance code 649405230

Summary

Main use
Treatment of gastrointestinal disorders (e.g., ulcers and gastritis), preanesthetic medication, and adjunctive treatment for Helicobacter pylori eradication
Who takes it
Adults
Adult dose
1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine per dose, taken orally twice daily in the morning and at bedtime. In clinical trials of up to 8 weeks, most ulcers healed within 8 weeks, although healing time may vary in some patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine per dose, taken orally twice daily in the morning and at bedtime. In clinical trials of up to 6 weeks, most ulcers healed within 6 weeks, although healing time may vary in some patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine once daily, taken orally at bedtime. In clinical trials of up to 2 weeks, most lesions healed within 2 weeks, although healing time may vary in some patients. 4. Combination therapy with antibiotics for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine per dose, twice daily.

Ingredients

Manufacturer
Youngil Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of gastrointestinal disorders (e.g., ulcers and gastritis), preanesthetic medication, and adjunctive treatment for Helicobacter pylori eradication

  • Gastric ulcers
  • duodenal ulcers
  • acute gastritis
  • chronic gastritis
  • peptic ulcers
  • gastroesophageal reflux disease
View approved original text

This medication is used for the treatment of gastric ulcers and duodenal ulcers. It also helps improve gastric mucosal damage caused by acute and chronic gastritis, and it enhances the treatment efficacy when used in combination with antibiotics for patients with peptic ulcers caused by Helicobacter pylori infection. It is also used preoperatively and helps alleviate symptoms of gastroesophageal reflux disease. Overall, it is effectively used to treat various conditions related to the stomach and digestive system.

How to take

Adult dose

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine per dose, taken orally twice daily in the morning and at bedtime. In clinical trials of up to 8 weeks, most ulcers healed within 8 weeks, although healing time may vary in some patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine per dose, taken orally twice daily in the morning and at bedtime. In clinical trials of up to 6 weeks, most ulcers healed within 6 weeks, although healing time may vary in some patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine once daily, taken orally at bedtime. In clinical trials of up to 2 weeks, most lesions healed within 2 weeks, although healing time may vary in some patients. 4. Combination therapy with antibiotics for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine per dose, twice daily.

Precautions

This medication should not be used by patients who are allergic to any of its ingredients. Additionally, since this medication contains lactose, patients with genetic issues such as galactose intolerance, Lapp lactase deficiency, and glucose-galactose malabsorption should not take it. Patients with a history of hypersensitivity to the drug, liver or kidney function problems, those on dialysis, and the elderly should use this medication with special caution. This drug can cause severe allergic reactions such as anaphylaxis or shock, so if symptoms like pallor, decreased blood pressure, or difficulty breathing occur after taking it, administration should be stopped immediately and healthcare professionals should be notified. Liver dysfunction or jaundice symptoms may appear, so regular liver function tests should be conducted, and if abnormalities are found, the medication should be discontinued, and treatment should be sought. This medication may have blood-related side effects such as agranulocytosis or thrombocytopenia, so if symptoms such as sore throat, systemic fatigue, or fever occur, immediate consultation with a healthcare professional is necessary. Rare serious adverse reactions such as skin rashes, convulsions, and heart problems have been reported, so if any abnormal symptoms occur, a hospital visit is required. Mild side effects such as abdominal pain, diarrhea, constipation, headaches, insomnia, dizziness, malaise, heat sensation, facial flushing, increased white blood cell count, elevated eosinophils, decreased white blood cell count, decreased red blood cell count, decreased hematocrit, elevated LDH, elevated TTT, proteinuria, increased BUN, elevated serum uric acid, increased Cl, delayed menstruation, increased Na, decreased K, gynecomastia, edema, fatigue, abdominal pain, dyspepsia, enteritis, and gastric ulcers may occur, but most are transient. Symptoms of malignancy may be masked during the use of this medication, so if weight loss, recurrent vomiting, or hematemesis occur, tests must be conducted. Particularly in cases where stomach cancer is suspected, the use of this medication should be stopped if malignancy is confirmed after initial testing. It is important to carefully observe the patient’s condition during treatment and not use it longer than necessary. The elderly may have decreased physical function, so dosage and administration intervals should be adjusted and used cautiously. In dialysis patients, drug concentration in the blood may increase, so treatment should begin with low doses and gradually adjusted. Pregnant women should take this medication only if the benefits outweigh the risks according to a physician's judgment, and breastfeeding women are advised against taking it as it may be excreted in breast milk. Safety for pediatric use has not been sufficiently confirmed, so it should be administered with caution to children. This medication should be kept out of reach of children and stored in its original container for safety.

Side effects

  • Shock
  • symptoms of anaphylaxis
  • facial pallor
  • hypotension
  • generalized rash
  • respiratory distress
  • hepatic dysfunction
  • jaundice
  • agranulocytosis
  • pharyngitis
Show 83 more
  • generalized malaise
  • fever
  • thrombocytopenia
  • pancytopenia
  • aplastic anemia
  • seizures
  • interstitial nephritis
  • Stevens-Johnson syndrome
  • Riel syndrome
  • rhabdomyolysis
  • heart block
  • inadequate contraction
  • constipation
  • diarrhea
  • hard stool
  • nausea
  • vomiting
  • abdominal bloating
  • loss of appetite
  • headache
  • insomnia
  • drowsiness
  • reversible confusional state
  • hallucinations
  • consciousness disturbance
  • dizziness
  • fever
  • sensation of heat
  • facial flushing
  • leukocytosis
  • eosinophilia
  • leukopenia
  • erythrocytopenia
  • decreased hematocrit
  • elevated ALT
  • elevated AST
  • elevated Al-P
  • elevated γ-GTP
  • elevated T-Bil
  • elevated LDH
  • elevated TTT
  • abnormal urinary protein
  • elevated BUN
  • elevated serum uric acid
  • elevated Cl
  • delayed stages of life
  • elevated Na
  • decreased K
  • gynecomastia
  • edema
  • malaise
  • glossitis
  • headache
  • chest pain
  • subdural hematoma
  • urticaria
  • skin rash
  • abdominal pain
  • dyspepsia
  • enteritis
  • gastric ulcer
  • erosive gastritis
  • duodenitis
  • distension
  • nasopharyngitis
  • upper respiratory infection
  • bronchopneumonia
  • tinea
  • carotid artery stenosis
  • cough
  • oropharyngeal pain
  • oropharyngeal discomfort
  • productive cough
  • fatigue
  • chest pain
  • limb pain
  • arthralgia
  • neck pain
  • itching
  • acne
  • contusion
  • insomnia
  • non-alcoholic steatohepatitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 degrees and 30 degrees Celsius.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.