All Down Capsule 60 mg (Orlistat)

Adult dose

The recommended dose of this medicine is 120 mg of orlistat per dose, taken orally 3 times daily with a fat-containing meal or within 1 hour after a meal. Patients should continue a nutritionally balanced, mildly hypocaloric diet in which approximately 30 % of calories are derived from fat. Daily intake of fat, carbohydrates, and protein should be distributed evenly among the three meals. This medicine may be omitted if a meal is skipped or contains no fat. Because this medicine may reduce the absorption of some fat-soluble vitamins and beta-carotene, patients are advised to take a multivitamin containing fat-soluble vitamins to ensure adequate nutrition. The vitamin supplement should be taken at least 2 hours before this medicine or at least 2 hours after it, such as at bedtime. Taking more than 120 mg per dose 3 times daily does not increase the efficacy of this medicine. Measurements of fecal fat indicate that the effect of this medicine appears 24 ∼ 48 hours after administration. After treatment is discontinued, fecal fat content generally returns to pretreatment levels within 48 ∼ 72 hours. The efficacy and safety of this medicine for periods exceeding 4 years have not been evaluated. Studies have not been conducted in patients with hepatic and/or renal impairment or in elderly patients.

Child dose

Studies have not been conducted in children under 12 years of age.

This medication should not be used in patients with chronic malabsorption syndrome or biliary obstruction. Furthermore, it should be avoided by individuals who are allergic to this drug or its ingredients, women who are pregnant or may become pregnant, and breastfeeding women. Liver damage has been reported rarely; therefore, if symptoms of liver dysfunction occur, consult a physician immediately and discontinue use. Patients with hyperoxaluria or calcium oxalate kidney stones should use this drug cautiously. Gastrointestinal side effects may occur frequently and can be exacerbated when taken with a high-fat meal. This drug can interfere with the absorption of fat-soluble vitamins and beta-carotene, so it is recommended to take vitamin supplements. Adverse reactions reported in clinical trials include abdominal pain, nausea, diarrhea, constipation, and fatty stools, most of which are mild and temporary. Serious adverse reactions such as liver damage or allergic reactions may occur; thus, if symptoms appear, notify medical personnel immediately. This drug may interact with certain medications; therefore, if taking other drugs, consult with a physician or pharmacist. It is safest for pregnant and breastfeeding women not to take this drug. Children over 12 years old are permitted to use it, and safety has not been established for children under 12. In case of overdose, 24-hour observation is required, and serious side effects are rare. This drug should be kept out of reach of children and should be stored protected from light and moisture.

• Fatty stools
• abdominal bloating and gas
• frequency of stools
• fatty/sfrothy stools
• fatty bowel movements
• increased bowel movements
• fecal incontinence
• abdominal pain/discomfort
• nausea
• infectious diarrhea

This medication should be stored in a tightly sealed container to protect it from air, light, and moisture, and it is advised to keep it in a cool place below 25 degrees. Proper storage will help maintain the effectiveness of the drug for a longer period.

Appearance

A yellow hard capsule containing white or off-white powder or granules

Package unit

Bottle packaging - 300 capsules/bottle, Bottle packaging - 30 capsules/bottle