Osolez (Cholecalciferol)

Adult administration

Administer 200,000 IU of cholecalciferol as an intramuscular injection. Elderly patients should receive 100,000 IU of cholecalciferol as an intramuscular injection. Ensure that the annual dosage does not exceed 600,000 IU of cholecalciferol.

Child administration

Administer 200,000 IU of cholecalciferol as an intramuscular injection.

This medication contains vitamin D; therefore, you must check the total vitamin D intake when using it with vitamin D fortified foods or other treatments. Regularly check calcium levels in the blood to ensure they do not become too high, and discontinue the medication if a certain threshold is exceeded. If calcium intake is high, it is essential to monitor blood and urine calcium levels more frequently. This medication should not be used by some patients, particularly those with allergies to its ingredients, hypercalcemia, kidney stones, poor kidney function, and women who are pregnant or breastfeeding. Side effects such as headaches, fatigue, muscle pain, indigestion, dehydration, increased blood pressure, kidney issues, skin rashes, etc., may occur while taking this medication, so consult a healthcare professional immediately if unusual symptoms arise. Blood vitamin D and parathyroid hormone levels should be regularly monitored to adjust the appropriate dose, especially for patients with reduced kidney function. During the administration of this medication, there may be interactions with certain anticonvulsants, steroids, diuretics, and antacids, so you must inform your healthcare provider about any other medications you are taking. Excessive vitamin D intake during pregnancy may cause adverse effects in the fetus; therefore, it is safest for pregnant and breastfeeding women to avoid using this medication. The safety and efficacy of this medication have not been adequately established for children under 12 years of age, so avoid using it in this population. In case of overdose, stop taking the medication immediately, reduce calcium intake, increase fluid intake, and seek medical assistance if necessary. Do not mix this medication with others, use it as soon as possible after opening, and dispose of any remaining medication after use. Store in a container that blocks light and maintain a room temperature of 1 to 30 degrees Celsius to preserve its efficacy.

Serious side effects

Kidney dysfunction, severe allergic reactions (hives, injection site hives), severe swelling, arrhythmia

Mild side effects

Headache, weakness, fatigue, muscle pain, loss of appetite, weight loss, growth retardation, nausea, vomiting, constipation, diarrhea, polydipsia, polyuria, dehydration, hypertension, calcium stones, tissue calcification in kidneys and blood vessels, excessive bone calcification, arrhythmia, mental symptoms, self-awareness impairment, joint pain, myasthenia, drowsiness, azotemia, hypersensitivity reactions, thirst, confusion, gas bloating, abdominal pain, metallic taste, dry mouth, rash, itching, granuloma at the injection site, injection site reactions

This medication may be sensitive to light; therefore, it should be stored in a container that blocks light. Additionally, it is important to store the medication at room temperature, specifically between 1 to 30 degrees Celsius. This will help maintain the medication's effectiveness for an extended period.

Appearance

A transparent liquid that is light yellow, contained in a brown glass ampoule as an injectable solution.

Package unit

0.5 milliliter/ampoule [0.5mL × 5 ampoules], 1 milliliter/ampoule [1mL × 5 ampoules]