Olmesartan Medoxomil/Amlo-dipine 5/40 mg Tablets

Adult dose

This medication should be taken once daily, one tablet with water, regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). The recommended dosage is as follows: - 5/20 mg: Given to patients whose blood pressure is not adequately controlled with Amlodipine 5 mg or Olmesartan Medoxomil 20 mg monotherapy. - 10/20 mg: Administered to patients whose blood pressure is not adequately controlled with Olmesartan Medoxomil 20 mg monotherapy.

Child dose

Safety and efficacy have not been established for pediatric patients under 18 years.

This medication can cause serious damage to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. It should not be taken if there is hypersensitivity to any of its components, or if the patient is pregnant or breastfeeding, has severe liver disease, aortic stenosis, bile duct obstruction, is undergoing kidney dialysis, is in a state of shock, or has certain types of diabetes. In patients who are volume or salt-depleted, hypotension may occur, so their condition should be closely monitored at the start of treatment, and appropriate measures should be taken if symptoms of hypotension arise. Acute hypotension may rarely occur due to its vasodilatory effects, so particular caution is needed in patients with aortic stenosis. In patients with severe heart disease, congestive heart failure, reduced kidney function, or impaired liver function, this medication should be used with caution. Side effects such as dizziness, headache, hypotension, orthostatic hypotension, edema, gastrointestinal disturbances, and rash may occur; if any unusual symptoms appear, consultation with a physician is advised. It is advisable for pregnant or breastfeeding women to avoid this medication, and if breastfeeding, they should either stop breastfeeding or discontinue the medication. Safety and efficacy have not been established in children under the age of 18, thus it is not recommended for this age group. Elderly patients may be more sensitive to this medication due to reduced liver, kidney, or heart function, hence starting with a low dose and careful monitoring is recommended. In case of overdose, hypotension and decreased cardiac function may occur, so immediate medical treatment should be sought. Taking this medication with grapefruit juice may excessively enhance the blood pressure-lowering effect, so it is advisable not to take them together. When combined with other medications, the potential for interactions exists, thus it is crucial to consult with a physician or pharmacist, especially with potassium-sparing diuretics, lithium, and non-steroidal anti-inflammatory drugs. Keep the medication out of the reach of children and store it in a tightly sealed container, avoiding direct sunlight and moisture.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of the skin or eyes), profound lethargy, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, and urine retention.

Mild side effects

• Dizziness
• headache
• reduced libido
• drowsiness
• sensory abnormalities
• decreased sensation
• nausea
• vomiting
• indigestion
• diarrhea

This medication can be sensitive to air and moisture, so it should be stored in a tightly sealed container. To maintain the efficacy of the medication, it is best to store it at room temperature, specifically between 1 to 30 degrees Celsius.

Appearance

Pale yellow round film-coated tablets

Package unit

28 tablets/box [14 tablets/PTP×2]