Medication info
Megalosartan Tablet (Losartan Potassium)

Megalosartan Tablet (Losartan Potassium)

Prescription medicationTablet경구
Ingredient · strength
Losartan Potassium›50mg / 1 tablet
Manufacturer / importer
(주)엘앤씨바이오
Appearance
White oval film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 202000343 · Approved 2020.01.21 · Insurance code 060500880

Summary

Main use
Improvement of hypertension and diabetic nephropathy
Who takes it
Adults · Children
Adult dose
This medication can be taken regardless of meals, but it is recommended to take it at the same time every day. For treating hypertension, the initial and maintenance dose of Losartan Potassium is a recommended oral administration of 50 mg once daily. If the therapeutic effect is insufficient, it can be increased to a divided oral administration of 100 mg once daily or 50 mg twice a day. For treatment of nephropathy in patients with hypertension and type 2 diabetes, the usual dose is...
Child dose
For children and adolescents aged 6 and older and weighing between 20 kg and less than 50 kg, a daily dose of 25 mg is recommended, with a maximum increase to 50 mg once daily. For patients weighing 50 kg or more, the...

Ingredients

Manufacturer
(주)엘앤씨바이오

Efficacy & effects

Improvement of hypertension and diabetic nephropathy

  • Hypertension
  • nephropathy in patients with type 2 diabetes
View approved original text

This medication is used to treat hypertension. It also helps to slow the progression of nephropathy in patients with type 2 diabetes who have hypertension. It is effective in managing kidney complications associated with hypertension and diabetes.

How to take

Adult dose

This medication can be taken regardless of meals, but it is recommended to take it at the same time every day. For treating hypertension, the initial and maintenance dose of Losartan Potassium is a recommended oral administration of 50 mg once daily. If the therapeutic effect is insufficient, it can be increased to a divided oral administration of 100 mg once daily or 50 mg twice a day. For treatment of nephropathy in patients with hypertension and type 2 diabetes, the usual dose is...

Child dose

For children and adolescents aged 6 and older and weighing between 20 kg and less than 50 kg, a daily dose of 25 mg is recommended, with a maximum increase to 50 mg once daily. For patients weighing 50 kg or more, the...

Precautions

This medication can cause serious harm to the fetus if taken during pregnancy, particularly during the second and third trimesters, so it should not be taken by women who are pregnant or may become pregnant. It is safer not to administer this drug to patients with severely impaired liver function or specific hereditary diseases. Elderly patients, patients with weakened kidney function, and patients with hyperkalemia should use this drug cautiously and should have regular blood tests and condition checks as directed by their physician. This medication lowers blood pressure, and symptoms of hypotension or shock may appear; therefore, any symptoms should be reported to healthcare professionals immediately. Occasionally, serious side effects such as allergic reactions, angioedema, hepatitis, or worsening kidney function may occur, so if any unusual symptoms arise, the medication should be stopped immediately and healthcare professionals consulted. This drug may interact with specific medications, requiring caution when taken in conjunction with potassium-sparing diuretics, potassium supplements, lithium, and non-steroidal anti-inflammatory drugs (NSAIDs). While taking this medication, regular checks should be conducted on blood pressure, kidney function, and electrolyte status, especially for elderly patients or those with kidney disease. Women who are pregnant or breastfeeding should avoid taking this drug, and if it is necessary to take it, they must consult a physician first. This medication should not be given to children, especially to those under 6 years old or very young patients with severely impaired kidney function. Overdose may lead to hypotension and cardiac rhythm abnormalities, so the prescribed dosage must be adhered to, and immediate emergency treatment should be sought in case of an overdose. When taking this medication, symptoms such as dizziness or drowsiness may occur, requiring caution when driving or operating machinery. This medication should be kept out of the reach of children and should not be transferred to other containers.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, angioedema (possible airway obstruction), severe allergic reactions, severe rash accompanied by fever, blisters, skin shedding, pain in oral/ocular mucosa, severe skin adverse reactions, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities with cough and fever, respiratory issues, yellowing of skin or eyes (jaundice), extreme lethargy.

Mild side effects

  • Muscle cramps
  • low back pain
  • leg pain
  • dizziness
  • congestion
  • upper respiratory infections
  • sinusitis
  • nausea
  • diarrhea
  • dyspepsia
Show 25 more
  • cough
  • sinus disorder
  • pharyngitis
  • myalgia
  • insomnia
  • headache
  • weakness/fatigue
  • swelling/edema
  • abdominal pain
  • chest pain
  • swelling of lips/eyelids
  • facial rash
  • palm skin peeling
  • hemolytic events
  • facial swelling
  • fever
  • orthostatic effects
  • syncope
  • angina pectoris
  • second-degree AV block
  • hypotension
  • palpitations
  • bradycardia
  • tachycardia
  • ventricular tachycardia.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be stored in a tightly closed container to protect it from exposure to air or moisture. It is recommended to maintain a storage temperature between 1°C and 30°C.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.