Amofin S Tablet 2.5 mg (Esamlodipine Besylate 2.5 Hydrate)

Adult dose

This medication should be taken with a sufficient amount of water. Administer 2.5 mg once daily as esamlodipine orally, with a maximum increase to 5 mg per day depending on the patient's response. Dosage can be adjusted appropriately based on symptoms.

This medication should not be administered to certain patients. For example, individuals allergic to this drug, its ingredients, or similar classes of medication should not use it. Women who are pregnant or may become pregnant, as well as those who are breastfeeding, should also refrain from using this medication. Patients in a state of cardiac shock or with severe valvular heart disease, unstable angina patients, recent myocardial infarction patients should avoid this drug. Additionally, great caution is advised for patients with severely diminished liver function and those with very low blood pressure. Patients with severe renal impairment, the elderly, acute heart failure patients, patients in hypertensive crises, and those with moderate hepatic dysfunction should be treated carefully. While taking this medication, various side effects may occur, with common symptoms including flushing and warmth, fatigue, or swelling. Patients may also experience heart palpitations, dizziness, headache, abdominal pain, nausea, and drowsiness. Rarely, allergic reactions such as skin rashes, itching, liver function abnormalities, reduction of blood cell counts, or psychological changes have been reported. If such symptoms occur, immediate consultation with a physician is recommended. Discontinuation of this medication suddenly can worsen symptoms, so dosage should be reduced gradually under a doctor's guidance, and it should not be stopped arbitrarily. Heart failure patients should be cautious, as the risk of pulmonary congestion as a side effect may increase when using this drug. Liver impaired patients may have a prolonged half-life of this drug in the body, requiring careful dosage adjustment and monitoring. The effects of this drug appear slowly and it is not suitable for emergency situations such as acute angina. When taking the medication, it should be ingested with plenty of water, and as blood pressure decreases, dizziness or drowsiness may occur, so caution is advised while driving or operating dangerous machinery. When taking this drug with other medications, there may be interactions, particularly with certain antibiotics, antihypertensives, heart medications, or drugs affecting liver function. Consultation with healthcare professionals is necessary if using concurrently. Taking this medication with grapefruit juice may lead to excessive antihypertensive effects, so it is advisable to avoid this combination. Women who are pregnant or breastfeeding should safely refrain from taking this medication, and breastfeeding should be discontinued while using this drug. In children, use is only recommended for those over 6 years old, and for the elderly, medications can remain in the body for a longer duration, so starting with a low dose and closely monitoring the condition is essential. In cases of overdose, severe hypotension, arrhythmias, or shock may occur, necessitating emergency treatment, and blood pressure and heart conditions should be continuously monitored if required.

Serious side effects

Urticaria, angioedema, toxic epidermal necrolysis, Stevens-Johnson syndrome, jaundice, hepatitis, liver dysfunction, sudden and severe headache, seizures, confusion, visual disturbances, paralysis, respiratory distress, difficulty breathing, severe swelling with elevated blood pressure, leukopenia, thrombocytopenia, shock, worsening heart failure, myocardial infarction, arrhythmias, sinoatrial block, atrioventricular block, cardiovascular circulation abnormalities, coma, confusion

Mild side effects

• Accompanied flushing with warmth
• fatigue
• swelling
• palpitations
• dizziness
• headache
• migraine
• weakness
• abdominal pain
• nausea

Store this medication in a tightly closed container to prevent air and moisture exposure. Also, avoid extremely hot or cold conditions and store it at room temperature between 1 and 30 degrees Celsius.

Appearance

Light yellow heart-shaped tablet with a scored line

Package unit

30 tablets/bottle, 300 tablets/bottle