Jinbrex Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this drug should be adjusted according to the patient and may be administered regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea: The initial recommended dose is 400 mg of celecoxib, with an additional 200 mg on the first day of administration if needed. From the second day onward, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may cause gastrointestinal bleeding if taken by individuals who consume alcohol daily, and consultation with a doctor or pharmacist is essential. This medication can increase the risk of cardiovascular thromboembolic events, such as myocardial infarction and stroke, regardless of the presence of cardiovascular diseases or risk factors, so it should be used at the minimum effective dose for the shortest period possible. There may be serious gastrointestinal side effects such as perforation, ulceration, and bleeding, so if gastrointestinal disturbance symptoms appear, immediate notification to medical personnel is required. This medication should not be administered to patients with certain allergy histories or severe liver impairment, kidney impairment, heart failure, or active peptic ulcers. Patients with impaired liver or kidney function, hypertension, heart failure, asthma, etc., should exercise special caution when using this medication and regular monitoring may be necessary. During treatment, abnormal reactions such as headache, dizziness, indigestion, skin rash, swelling, and hypertension may occur, and abnormal symptoms should be reported immediately. This medication can interact with other drugs, so it is essential to inform the physician if taking blood pressure medications, anticoagulants, antidepressants, lithium, methotrexate, etc. Women who are pregnant or may become pregnant and nursing mothers should not take this medication, and women planning for pregnancy should be cautious as well. The elderly may be at risk for impaired kidney and heart functions, so more careful monitoring is required when using this medication. Patients taking this medication long-term should undergo regular blood tests and liver/kidney function tests, and if any abnormalities are found, discontinuation of the medication may be necessary. Dizziness or drowsiness may occur after taking this medication, so caution should be exercised when driving or operating machinery. When storing the medication, keep it out of reach of children and do not transfer it to other containers.

Gastrointestinal hemorrhage, cardiovascular thrombotic response, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcer, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, kidney stones, urinary incontinence, urinary tract infection, visual clouding, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal impairment, acute renal failure, interstitial nephritis, headache, leg cramps, sensory loss, migraine, neuralgia, neuropathy, sensory anomalies, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, worsening allergies, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, septic shock, sudden death, anaphylactoid reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, menstrual disorders, anaphylactic reaction, hallucination, vasculitis, pulmonary embolism, acute renal failure, hyponatremia, photosensitive reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized bullous fixed drug eruption, fixed drug eruption, female infertility, chest pain, thirst, ulcerative stomatitis, gastritis, allergy, low back pain, hyperlipidemia, diabetes, weight gain, fracture, arthralgia, RA factor positive, herpes zoster, pneumonia, dyspnea, elevated ALT, hearing loss, dry mouth, stomatitis, retrosternal pain, angular stomatitis, intestinal obstruction, bowel perforation, gastrointestinal bleeding, hemorrhagic colitis, esophageal perforation, intestinal obstruction, alveolar osteitis after tooth extraction, bowel anastomosis ulcer, melena, glossitis, aphthous stomatitis, oral mucosal vesicle formation, numbness of the mouth, oral pain

This medication should be stored in a sealed container to prevent air exposure and is best kept at room temperature between 15 degrees and 30 degrees Celsius. This will help maintain the drug's effectiveness.

Appearance

A white capsule filled with a powder that is white to pale yellow with a yellow band on both top and bottom

Package unit

30 capsules/bottle, 100 capsules/bottle