Silverbig Sajeong (Memantine Hydrochloride)

Adult dose

Treatment must be initiated by a physician experienced in the diagnosis and treatment of Alzheimer's dementia and should only be started if a caregiver can regularly check the patient's medication intake. This medication can be taken regardless of food intake. Dosage increase: The maximum daily dose is 20mg, and to minimize the risk of adverse reactions, the dosage should be increased by 5mg weekly over the first 3 weeks. First week (Day 1-7): Administer 5mg daily for 7 days. Second week (Day 8-14): Administer 10mg daily (5mg twice a day) for 7 days. Third week (Day 15-21): Administer 15mg daily (10mg in the morning, 5mg in the evening) for 7 days. From the fourth week: Administer 20mg daily (10mg twice a day). Maintenance dose: The recommended maintenance dose is 20mg daily (10mg twice a day).

This medication should not be used in patients with an allergy to its components. It should be avoided in patients with severe hepatic dysfunction or severely reduced renal function. It should be used with caution in patients with epilepsy or a history of seizures, and it should not be taken together with other drugs that have similar effects as this may increase side effects. Patients with changes in urinary acidity should be careful while taking this medication, and there is insufficient data for patients with heart disease or uncontrolled hypertension, so caution is advised. During the use of this medication, side effects such as dizziness, headache, constipation, drowsiness, and hypertension may occur, and if symptoms are severe, consultation with a healthcare professional is necessary. It may interact with other medications, so any drugs being taken should be reported, particularly when taken with antipsychotics, skeletal muscle relaxants, and anticoagulants. Women who are pregnant or may become pregnant should carefully consider the risks and benefits of using this medication, and those who are breastfeeding are advised to discontinue breastfeeding. It is advisable not to use this medication in children under 18 years of age, as safety and efficacy have not been established. In case of overdose, central nervous system symptoms and gastrointestinal symptoms may appear, so immediate medical attention should be sought. This medication may slow the response rate of the patient, so care is needed when driving or operating machinery. Lastly, this medication should be kept out of reach of children, and it is important not to transfer it to other containers to maintain its quality.

Serious side effects

• Seizures
• heart failure
• venous thrombosis/thromboembolism
• respiratory distress
• pancreatitis
• drug hypersensitivity

Mild side effects

• Dizziness
• headache
• constipation
• drowsiness
• hypertension
• confusion
• hallucinations
• psychiatric reactions
• balance disorders
• gait abnormalities

This medication should be stored in a tightly closed container to protect it from air and moisture, and the storage temperature should be kept at room temperature between 1 to 30 degrees Celsius. In other words, it should not be kept in excessively hot or cold places; storing it safely at the appropriate temperature is essential for maintaining its efficacy.

Appearance

White rectangular film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle