Medication info

Lafutizene Tablet 10mg (Lafutidine)

Prescription medicationTabletExpired
Ingredient · strength
Lafutidine›10mg / 1 tablet
Manufacturer / importer
Celix Co., Ltd.
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Expired

MFDS item code 202000210 · Approved 2020.01.14

This product's status changed to Expired on 2025.01.14. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of gastrointestinal disorders (ulcers, gastritis, etc.); preanesthetic medication; combination therapy for Helicobacter pylori eradication
Who uses it
Adults
Adult dosage
1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and at bedtime. In clinical trials in which treatment was given for up to 8 weeks, most ulcers healed within 8 weeks, although the healing period may occasionally vary from patient to patient. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and at bedtime. In clinical trials in which treatment was given for up to 6 weeks, most ulcers healed within 6 weeks, although the healing period may occasionally vary from patient to patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily at bedtime. In clinical trials in which treatment was given for up to 2 weeks, most lesions healed within 2 weeks, although the healing period may occasionally vary from patient to patient. 4. Combination therapy with antibiotics in patients with peptic ulcers infected with Helicobacter pylori: Administer 20mg of lafutidine, 500mg of clarithromycin, and 1000mg of amoxicillin twice daily for 7 or 14 days. 5. Premedication: The usual dose is 10mg of lafutidine orally per dose, for 2 doses (at bedtime on the day before surgery and 2 hours before administration of anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine orally twice daily.

Ingredients

Manufacturer
Celix Co., Ltd.

Efficacy & effects

Treatment of gastrointestinal disorders (ulcers, gastritis, etc.); preanesthetic medication; combination therapy for Helicobacter pylori eradication

  • Gastric ulcer
  • duodenal ulcer
  • acute gastritis
  • chronic gastritis
  • peptic ulcer
  • gastroesophageal reflux disease
View approved original text

This medication is effective for the treatment of gastric ulcer and duodenal ulcer, improving gastric mucosal damage caused by acute and chronic gastritis. Additionally, it is used together with antibiotics for patients with peptic ulcers caused by Helicobacter pylori infection to enhance therapeutic effects. It can also be utilized as premedication before surgery or procedures. It is used to treat gastroesophageal reflux disease, alleviating symptoms and protecting the mucosa. As such, it is widely used for the treatment and symptom relief of various gastrointestinal diseases.

Dosage and Administration

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and at bedtime. In clinical trials in which treatment was given for up to 8 weeks, most ulcers healed within 8 weeks, although the healing period may occasionally vary from patient to patient. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and at bedtime. In clinical trials in which treatment was given for up to 6 weeks, most ulcers healed within 6 weeks, although the healing period may occasionally vary from patient to patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily at bedtime. In clinical trials in which treatment was given for up to 2 weeks, most lesions healed within 2 weeks, although the healing period may occasionally vary from patient to patient. 4. Combination therapy with antibiotics in patients with peptic ulcers infected with Helicobacter pylori: Administer 20mg of lafutidine, 500mg of clarithromycin, and 1000mg of amoxicillin twice daily for 7 or 14 days. 5. Premedication: The usual dose is 10mg of lafutidine orally per dose, for 2 doses (at bedtime on the day before surgery and 2 hours before administration of anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine orally twice daily.

Precautions

This medication should not be taken by individuals allergic to any of its components. It contains lactose, so individuals with a genetic inability to digest lactose should not take this medication. Those with a history of drug allergies should take this medication with caution, and individuals with liver or kidney function issues should also be careful. Particularly, patients undergoing dialysis and the elderly should exercise greater caution when taking this medication. This medication can rarely cause severe allergic reactions, liver dysfunction, or reduction in blood cell count; if such symptoms occur, discontinue use immediately and consult a healthcare professional. Headache, dyspepsia, constipation, diarrhea, nausea, vomiting, and abdominal bloating may occur; if symptoms are severe or persistent, consult a physician. Symptoms of malignancy may be concealed while taking this medication, therefore, if there are symptoms such as weight loss, recurrent vomiting, or hematemesis, it is essential to undergo examination. Elderly patients may have decreased bodily function; thus, dosage and intervals should be adjusted carefully, and their condition should be monitored closely. Women who are pregnant or may become pregnant should take this medication under a doctor's discretion, and breastfeeding women should avoid it as it may be excreted in breast milk. The safety of this medication in children has not been fully established, so it is advisable not to use it in children. This medication should be stored out of reach of children and should be kept in its original container to maintain the quality of the medication.

Side effects

  • Shock
  • Anaphylactic symptoms
  • Facial pallor
  • Hypotension
  • Systemic rash
  • Dyspnea
  • Hepatic dysfunction
  • Jaundice
  • Agranulocytosis
  • Pharyngitis
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  • General malaise
  • Fever
  • Thrombocytopenia
  • Pancytopenia
  • Aplastic anemia
  • Seizures
  • Interstitial nephritis
  • Stevens-Johnson syndrome
  • Riele syndrome
  • Rhabdomyolysis
  • Heart block
  • Decreased contraction
  • Constipation
  • Diarrhea
  • Hard stools
  • Nausea
  • Vomiting
  • Abdominal bloating
  • Reduced appetite
  • Headache
  • Insomnia
  • Drowsiness
  • Reversible confusional state
  • Hallucinations
  • Consciousness disturbance
  • Dizziness
  • Fever
  • Sensation of heat
  • Facial flushing
  • Leukocytosis
  • Elevated eosinophils
  • Leukopenia
  • Erythrocytopenia
  • Decreased hematocrit
  • Increased ALT
  • Increased AST
  • Increased Al-P
  • Increased γ-GTP
  • Increased T-Bil
  • Increased LDH
  • Increased TTT
  • Abnormal urine protein
  • Increased BUN
  • Elevated serum uric acid
  • Elevated Cl
  • Delayed birth
  • Increased Na
  • Decreased K
  • Gynecomastia
  • Edema
  • Fatigue
  • Glossitis
  • Headache
  • Urticaria
  • Skin rash
  • Abdominal pain
  • Dyspepsia
  • Enteritis
  • Gastric ulcer
  • Erosive gastritis
  • Duodenitis
  • Distension
  • Nasopharyngitis
  • Upper respiratory infection
  • Bronchopneumonia
  • Tinea
  • Carotid artery stenosis
  • Cough
  • Oropharyngeal pain
  • Oropharyngeal discomfort
  • Wet cough
  • Fatigue
  • Chest pain
  • Limb pain
  • Joint pain
  • Cervical pain
  • Itching
  • Acne
  • Contusion
  • Insomnia
  • Non-alcoholic fatty liver disease

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent air or moisture from entering. Additionally, avoid storing it in excessively hot or cold places, and it is best to keep it at room temperature between 1°C and 30°C.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.