Coxgreen Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered regardless of meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) : Take 200 mg of celecoxib once daily, or 100 mg per dose twice daily. 2. Rheumatoid arthritis : Take 100 mg or 200 mg of celecoxib per dose twice daily. 3. Ankylosing spondylitis (AS) : Administer 200 mg of celecoxib once daily, or 100 mg per dose twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, another treatment should be considered. 4. Acute pain and primary dysmenorrhea : The initial recommended dose is 400 mg of celecoxib; if necessary, an additional 200 mg may be administered on the first day of treatment. From the second day of treatment, the recommended dose as needed is 200 mg per dose twice daily. ○ Patients with hepatic impairment : For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may increase the risk of gastrointestinal bleeding in people who regularly consume three or more alcoholic drinks per day; therefore, it is essential to consult a physician or pharmacist. This medication can increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke, so it is important to use the lowest effective dose for the shortest duration possible. Particularly, patients with a history of cardiovascular disease or risk factors should be closely monitored for cardiovascular symptoms, and if any chest pain or shortness of breath occurs, they should immediately inform medical staff. This medication may increase the risk of gastrointestinal perforation, ulcers, and bleeding, so patients who are elderly or have a history of gastrointestinal disease should be particularly cautious when taking it. Symptoms of gastrointestinal bleeding include epigastric pain, dyspepsia, black stools, and hematemesis, so if these symptoms occur, one should visit a hospital immediately. This medication should not be administered to those with a history of specific allergies, severe liver disease, renal impairment, active peptic ulcer, congestive heart failure, pregnant women, or breastfeeding women. Patients with impaired liver or kidney function, or those with a history of hypertension, heart failure, or asthma should be carefully monitored and managed while taking this medication. Various adverse reactions may occur during the use of this medication, such as headache, dizziness, dyspepsia, edema, skin rash, hypertension, and respiratory distress; thus, if any symptoms appear, one should consult medical staff. Especially if symptoms such as rash, blisters, severe itching, or fever occur, medication should be stopped immediately, and a hospital visit is necessary. This medication is metabolized in the liver, and blood concentrations may change when taken with specific drugs, so it is important to discuss potential interactions with other medications with a physician. Pregnant women or women who may become pregnant should not take this medication, and if pregnancy is discovered while taking it, treatment should be stopped immediately. Women who are breastfeeding should also either stop breastfeeding or consult a physician when taking this medication. Elderly patients are at a higher risk for decreased liver and kidney function, requiring extra caution when taking this medication, and dosage adjustments may be necessary. Patients taking this medication long-term should have regular blood tests and liver and kidney function tests to check for abnormalities. In cases of overdose, symptoms such as nausea, vomiting, drowsiness, and lethargy may occur, and appropriate treatment should be sought from a medical institution immediately. This medication should be kept out of reach of children and should not be transferred to other containers.

Gastrointestinal bleeding, cardiovascular thromboembolism, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, abdominal distension, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, frequency, kidney stones, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urinary blood, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitive reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized pustular exanthema, exfoliative dermatitis, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, chest pain, dyspepsia, diarrhea, headache, dizziness, constipation, anemia, polydipsia, ulcerative stomatitis, gastritis, allergy, low back pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, positive rheumatoid factor, shingles, pneumonia, dyspnea, elevated ALT, hearing loss, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, malaise, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reaction, angioedema, headache, dizziness, leg cramps, hypertonia, sensory deficits, migraine, neuralgia, neuropathy, perceptual disturbances, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, upper respiratory infection, herpes simplex, wound infection, gingivitis, herpes simplex, shingles, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorder, ovarian cysts, hearing impairment, ear abnormalities, ear pain, tinnitus, hearing loss, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, elevated serum sodium, elevated serum potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, elevated NPN, increased creatinine, increased alkaline phosphatase, weight gain, anorexia, elevated LDH, hypoglycemia, hyponatremia, synovial sacs, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical strain, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, back pain, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, anemia, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic esophagitis, contact dermatitis, injection site reactions, skin nodules, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urinary blood, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis

This medication should be stored in a tightly closed container to prevent air and moisture from entering. The appropriate storage temperature is between 15 and 30 degrees Celsius (59 to 86 degrees Fahrenheit). Proper storage will help maintain the effectiveness of the medication.

Appearance

A white capsule filled with a powder that is white to light yellow, with blue stripes at the top and bottom.

Package unit

Bottle packaging - 30 capsules/bottle, Bottle packaging - 100 capsules/bottle