Gatopride Tablets (Itopride Hydrochloride)

Adult dose

○ Adults: Administer itopride hydrochloride 50 mg orally 3 times daily before meals. The dose may be reduced as appropriate according to symptoms.

This medication should not be used by patients who have an allergy to this medication or its ingredients, or who have previously experienced hypersensitivity reactions. Also, it should not be administered to patients for whom stimulation of gastrointestinal motility would be harmful, such as those with gastrointestinal bleeding, mechanical obstruction, or perforation. This medication contains lactose, so it should not be used in patients with genetic conditions that prevent the digestion of lactose. During the use of this medication, serious allergic reactions such as shock or anaphylaxis may occur, requiring careful monitoring. It is necessary to periodically check liver health due to the possibility of liver dysfunction or jaundice symptoms. Gastrointestinal symptoms such as nausea, diarrhea, constipation, and abdominal pain can occur, as well as neurological symptoms like headache, anxiety, sleep disturbances, and dizziness. Endocrine anomalies such as gynecomastia or increased prolactin levels may occur, so patients should report any such symptoms immediately. There may be adverse blood-related reactions like thrombocytopenia or leukopenia, necessitating blood tests to monitor the condition. It can impact kidney function, so it is important to check blood levels of BUN and creatinine. Rarely, hypersensitivity reactions like skin rash and itching may occur, requiring cessation of the medication upon symptom onset. This medication enhances acetylcholine activity, so it should be used with this consideration in mind, and long-term use should be avoided if gastrointestinal symptoms do not improve. When taken with anticholinergics, the effect of this medication may be reduced, so caution regarding dosing intervals is advised. Women who are pregnant or may become pregnant should be cautious with this medication since its safety has not been established; it should only be used when necessary. During breastfeeding, this medication may be secreted in breast milk, so use should be avoided if possible, and if unavoidable, breastfeeding should be discontinued. The safety in children has not been sufficiently confirmed, so it should be administered carefully to pediatric patients. Elderly patients may exhibit increased adverse reactions due to decreased physical function, requiring careful observation and potential dosage adjustments or discontinuation based on symptoms. This medication should be stored out of reach of children, and transferring it to another container may cause accidents or deterioration in quality, so caution is required.

• Shock
• anaphylactic symptoms
• hypotension
• dyspnea
• laryngeal edema
• urticaria
• pallor
• sweating
• liver dysfunction
• jaundice

This medication can be sensitive to air and moisture, so it must be stored in a tightly sealed container. Additionally, avoid excessively hot or cold places, and it's advisable to store at room temperature between 1 to 30 degrees Celsius.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle