Biatin Tablet 100 mg (Sitagliptin Hydrochloride Hydrate)

Adult dosage

This medication is administered as a single dose of 100 mg once a day, either as monotherapy or in combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. Dosage adjustment for patients with renal impairment: 1. Mild renal impairment (glomerular filtration rate [eGFR] ≥ 60 and < 90 mL/min/1.73 m2): No dosage adjustment is necessary. 2. Moderate renal impairment (glomerular filtration rate [eGFR] ≥ 45 and < 60 mL/min/1.73 m2): No dosage adjustment is necessary.

This medication can occasionally cause serious allergic reactions, so if symptoms such as skin rash, difficulty breathing, swelling of the face or neck occur within three months of administration, discontinue use immediately and seek medical attention. During the use of this medication, severe pancreatic inflammation known as pancreatitis may occur, so if abdominal pain, vomiting, or severe abdominal pain arise, inform your doctor immediately. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, and it should not be administered if there is an allergy to this medication or its components. Patients with reduced kidney function need to have the dosage of this medication adjusted, so they should undergo kidney function tests and take it according to their doctor's instructions. While taking this medication, side effects such as upper respiratory tract infections, nasopharyngitis, headache, diarrhea, nausea, and more may occur. When taken with other hypoglycemic agents or insulin, the risk of hypoglycemia may increase, so be careful for symptoms of hypoglycemia and adjust the dosage with the advice of a doctor as needed. Rare side effects such as arthralgia or skin blisters have been reported, so if severe joint pain or blisters or rashes appear on the skin, notify your doctor immediately. Pregnant or breastfeeding women are advised not to use this medication, and safety has not been established in children and adolescents under 18 years of age. Elderly patients may have reduced kidney function, so regular kidney function tests should be conducted before and during the use of this medication. In case of overdose, seek medical attention immediately for appropriate treatment, and this medication can be partially removed by hemodialysis, so dialysis treatment may be considered if necessary.

Serious side effects

Urticaria, severe hypersensitivity reactions (anaphylaxis, angioedema), Stevens-Johnson syndrome, exfoliative skin diseases, acute pancreatitis (fatal/non-fatal hemorrhagic or necrotizing pancreatitis), severe and debilitating arthralgia, bullous pemphigoid, acute renal failure, pneumonia, diabetic complications, metabolic acidosis, cardiac arrest, severe hypoglycemia

Mild side effects

• Upper respiratory tract infection
• nasopharyngitis
• headache
• dyspepsia
• dizziness
• diarrhea
• nausea
• constipation
• myalgia
• limb pain

This medication should be stored in a tightly sealed container to prevent air from entering, and it is recommended to keep it at room temperature between 1°C and 30°C. Proper storage helps maintain the efficacy of the medication.

Appearance

Orange, round, biconvex, film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP×3EA]