Rasagiline Tablets 0.5 mg (Rasagiline mesylate)

Adult dose

This medicine is administered orally once daily to adults as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended starting dose for patients taking levodopa is 0.5mg once daily. If well tolerated but an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

This medication should not be used in patients who are allergic to its active ingredient or other components. Also, patients who are currently taking or have stopped taking other MAO inhibitors within the last 2 weeks should not use this medication. Patients who are taking or have stopped taking specific medications such as pethidine, tramadol, or dextromethorphan within the last 2 weeks should also avoid this medication. Patients with moderate to severe liver dysfunction should not be administered this medication. During administration, various adverse reactions may occur, and if symptoms such as headache, depression, hallucinations, dizziness, dermatitis, or arthralgia appear, it is important to consult a healthcare professional immediately. Particular care should be taken if this medication is taken in conjunction with levodopa, as motor dyskinesia symptoms may worsen. This medication may affect blood pressure; therefore, if there are symptoms of hypertension or hypotension, consult a physician. Impulse control disorders may arise, so it is essential to report any changes such as compulsive behaviors, pathological gambling, or increased libido. Patients with decreased liver function should be particularly cautious when starting this medication, and dosage should be discontinued if liver function worsens. This medication may cause drowsiness or sudden sleep, so caution is necessary when driving or operating hazardous machinery. There are many potential interactions with other medications; thus, it is crucial to consult a doctor, especially when taken together with MAO inhibitors, antidepressants, sympathomimetics, or specific analgesics. Caution is advised during pregnancy or breastfeeding, and expert consultation may be necessary if needed. It is recommended not to use in children under 18 years old as safety and efficacy have not been confirmed. Overdosage can result in serious side effects, so it is essential to adhere to the prescribed dosage, and immediate medical attention should be sought in the event of overdose. This medication should be stored out of reach of children, kept in a suitable temperature environment, and should not be transferred to another container.

• Influenza
• Skin cancer
• Leukopenia
• Allergy
• Decreased appetite
• Depression
• Hallucinations
• Headache
• Cerebrovascular accident
• Conjunctivitis

This medication should be stored in a tightly closed container to protect it from air and moisture. The appropriate storage temperature is a cool place between 1 degree and 25 degrees.

Appearance

A white or almost white, flat circular tablet with bevelled edges, engraved with “RST” on the top side and “0.5” on the bottom side.

Package unit

30 tablets/box [10 tablets/PTP * 3]