Medication info
Rasagiline Mesylate 1 mg Tablets

Rasagiline Mesylate 1 mg Tablets

Prescription medicationTabletOral
Ingredient · strength
Rasagiline Mesylate›1.56mg / 1 tablet
Manufacturer / importer
Korea Pharmaceutical Co., Ltd.
Appearance
White or nearly white flat round tablets with corners, scored on one side with "RST" on the upper side and "1" below.
Packaging
30 tablets/box [10 tablets/PTP * 3]
Approval status
Active

MFDS item code 201908719 · Approved 2019.12.31 · Insurance code 642803270

Summary

Main use
Treatment of idiopathic Parkinson’s disease
Who takes it
Adults
Adult dose
This medicine is administered orally once daily to adults as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended starting dose for patients taking levodopa is 0.5mg once daily. If well tolerated but an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Ingredients

Manufacturer
Korea Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of idiopathic Parkinson’s disease

  • Idiopathic Parkinson's disease
  • motor fluctuations.
View approved original text

This medicine is used to treat idiopathic Parkinson's disease. Initially, it is used alone or in combination with dopamine agonists to help alleviate symptoms. It is also utilized as an adjunct therapy to improve motor fluctuations that occur at the end of the dose (end of dose fluctuations). This helps maintain more stable motor functions in patients and improves the quality of daily life. Overall, it effectively supports symptom management for patients with Parkinson's disease.

How to take

Adult dose

This medicine is administered orally once daily to adults as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended starting dose for patients taking levodopa is 0.5mg once daily. If well tolerated but an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Precautions

This medication should not be used by individuals who are allergic to the active ingredient or other components. Those who are taking other MAO inhibitors or have stopped taking them within the last 2 weeks should also not use this medication. Particularly, individuals taking or having recently stopped medications such as pethidine, tramadol, or dextromethorphan should avoid this medication. Patients with moderate or severe liver dysfunction should not take this medication. Various side effects such as flu symptoms, skin cancer, leukopenia, allergy, depression, hallucinations, headaches, dizziness, angina, rhinitis, dermatitis, myalgia, arthralgia, nausea, vomiting, constipation, dry mouth, diarrhea, hernia, infection, falls, weight loss, drowsiness, movement disorders, hallucinations, insomnia, etc., may occur while taking this medication. Care should be taken especially when using this medication in conjunction with levodopa as movement disorders or hypotension may occur. Additionally, patients taking dopaminergic therapies may experience impulse control disorders or sudden drowsiness during the day, thus regular monitoring of their condition is necessary. Pregnant or breastfeeding women should exercise caution when using this medication, and safety has not been established in children under 18 years of age. No separate dosage adjustment is required for the elderly. In cases of overdose, hypertensive crises, serotonin syndrome, and hypomania may occur, so immediate medical assistance is required. Taking this medication together with other MAO inhibitors, antidepressants, sympathomimetics, pethidine, tramadol, and dextromethorphan can cause serious side effects, so it is essential to consult a professional. Smokers need to be cautious as the serum concentration of this medication may be reduced. Drowsiness or sleep attacks may occur while driving or operating machinery, so caution is needed in case symptoms arise.

Side effects

  • influenza
  • skin cancer
  • leukopenia
  • allergy
  • loss of appetite
  • depression
  • hallucinations
  • headache
  • cerebrovascular accident
  • conjunctivitis
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  • dizziness
  • angina
  • myocardial infarction
  • rhinitis
  • abdominal distension
  • dermatitis
  • vesicular rash
  • musculoskeletal pain
  • neck pain
  • arthritis
  • urgency
  • fever
  • fatigue
  • nausea
  • peripheral edema
  • falls
  • joint pain
  • low back pain
  • cough
  • insomnia
  • upper respiratory infection
  • orthostatic hypotension
  • constipation
  • vomiting
  • dry mouth
  • diarrhea
  • abdominal pain
  • indigestion
  • hernia
  • infection
  • gingivitis
  • accidental injury
  • weight loss
  • tendinitis
  • dyskinesia
  • drowsiness
  • sensory abnormalities
  • ataxia
  • muscle tension abnormalities
  • myasthenia
  • anorexia
  • abnormal dreams
  • respiratory distress
  • rash
  • hyperhidrosis
  • hematoma
  • bleeding
  • melanoma
  • confusion
  • carpal tunnel syndrome
  • balance disorder
  • hallucinations
  • hypertension
  • pathological gambling
  • increased libido
  • hypersexuality
  • compulsive buying or shopping
  • binge eating
  • compulsive eating
  • compulsive behavior
  • obsessive thinking
  • impulsive behavior
  • hypotension
  • excessive drowsiness
  • acute renal failure
  • malignant hyperthermia
  • spinal fracture
  • rib fracture
  • tendon injury
  • pelvic fracture
  • leg fracture
  • upper limb fracture
  • back pain
  • knee joint replacement
  • intervertebral disc herniation
  • hypoglycemia
  • weight loss
  • dysuria
  • orthostatic hypotension
  • general weakness
  • pulmonary tuberculosis
  • hallucinations
  • semicoma
  • gait disturbance
  • ocular motor seizures
  • facial paralysis
  • spinal canal stenosis
  • worsening of Parkinson's disease
  • subdural hemorrhage
  • pneumonia
  • myalgia
  • osteoporosis
  • limb weakness
  • concussion
  • unspecified abrasion
  • laceration
  • scoliosis
  • thirst
  • hematuria
  • polyuria
  • vaginitis
  • conjunctival injection
  • diplopia
  • visual impairment
  • skin hypertrophy
  • palpitations
  • arrhythmia
  • gastrointestinal discomfort
  • gastroesophageal reflux
  • excessive gastric secretion
  • irritable bowel syndrome
  • fissured tongue
  • increased bowel movement frequency
  • unspecified gastrointestinal disease
  • esophagitis
  • hyperacidity
  • gastroesophageal reflux
  • gastric irritation
  • gastritis
  • bowel motility disorder
  • periodontitis
  • Helicobacter pylori gastritis
  • anemia
  • leg pain
  • chest pain
  • syncope
  • periorbital edema
  • facial flushing
  • pain
  • delusion
  • sleep disorder
  • aggression
  • amnesia
  • memory impairment
  • lethargy
  • sleep talking
  • psychosexual disorders
  • skin tingling
  • tremor
  • freezing phenomenon
  • limb shaking
  • polysynaptic myoclonus
  • leg cramps
  • diarrhea
  • tremor
  • stuttering
  • vocal disorders
  • vocal cord paralysis
  • language disorder
  • itching
  • urticaria
  • abscess
  • hair loss
  • bruise
  • abnormal sputum
  • increased sputum
  • cold
  • bronchitis
  • chest burning
  • fatigue
  • worsened tremor

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, and it is important to maintain a storage temperature between 1°C and 25°C. This ensures the safe efficacy of the medication.

Appearance and packaging

Appearance

White or nearly white flat round tablets with corners, scored on one side with "RST" on the upper side and "1" below.

Package unit

30 tablets/box [10 tablets/PTP * 3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.