Tragliem Duo Tablets 2.5/1000 mg

Adult dose

This drug is administered twice a day with meals. 1. If currently not being treated with metformin: Take this drug 2.5/500 mg, 1 tablet twice a day, and can be increased up to 2.5/1000 mg, 1 tablet twice a day. 2. If adequate blood sugar control cannot be achieved with metformin alone: Linagliptin 2.5 mg twice a day and the existing dosage of metformin.

This drug is used for the treatment of diabetes and helps to control blood sugar levels. However, there are certain cases in which it should not be used. For example, it should not be taken if there is an allergy to the components of this drug, or in cases of type 1 diabetes, lactic acidosis, or severe kidney or liver disease. Additionally, it is advisable not to use this drug in situations where the physical condition may rapidly deteriorate, such as severe infections, dehydration, heart failure, or acute myocardial infarction. It is also recommended that pregnant or nursing women do not take this drug. This drug may cause hypoglycemia, so blood sugar levels should be closely monitored, especially when used with other hypoglycemic agents. A rare side effect called lactic acidosis may occur, which is serious; if symptoms such as abdominal pain, muscle pain, malaise, or difficulty breathing occur, medical consultation should be sought immediately. Patients with reduced kidney function should have kidney function tests before taking this drug and should regularly check kidney function. This drug should also be used cautiously in patients with liver dysfunction and any symptoms of liver dysfunction should be reported to medical personnel. Additionally, rare side effects like acute pancreatitis or bullous pemphigoid (blisters on the skin) have been reported, and if such symptoms appear, use should be discontinued immediately and a doctor should be consulted. This drug may interact with other medications, so patients must inform healthcare providers about any other medications they are taking. Particularly, caution is needed when taken with medications that may affect kidney function or blood sugar levels. Women who are pregnant or planning to become pregnant should avoid this drug and consult other methods for blood sugar control. Similarly, nursing mothers should consult with healthcare professionals before taking this drug. It is advisable not to use this drug in children under 10 years of age since safety and efficacy have not been established. In elderly patients, since reduced kidney function is common, it's important to regularly monitor kidney function and to start at the lowest effective dose when using this drug. In case of overdose, serious side effects like lactic acidosis may occur, so the prescribed dose should be strictly followed, and if side effects are suspected, the hospital should be visited immediately. This drug should be stored out of reach of children, kept away from moisture, and it is advisable not to transfer it to other containers.

Serious side effects

Hives, angioedema (severe swelling), chest tightness, difficulty breathing, diarrhea, pancreatitis, bullous pemphigoid, lactic acidosis, abnormal liver function (hepatitis, abnormal liver function tests, jaundice), acute myocardial infarction, heart failure, angina pectoris, acute myocardial infarction, unstable angina, cardiac arrest, asthma attacks, difficulty breathing, severe rash with fever, blistering, skin peeling, oral/ocular mucosal pain

Mild side effects

Nasopharyngitis, hypersensitivity, vitamin B12 decrease and deficiency, hypoglycemia (when used with sulfonylureas), dysgeusia, cough, decreased appetite, diarrhea, constipation (when used with insulin), nausea, vomiting, abdominal pain, oral ulcer formation, abnormal liver function tests, hepatitis, pruritus, erythema, rashes, severe joint pain with disability, rhabdomyolysis, lipase increase, amylase increase, angioedema, dyspepsia, upper abdominal pain

This drug is sensitive to air and moisture, so it should be stored in a tightly sealed container. The storage temperature should be maintained between 1 degree and 30 degrees Celsius.

Appearance

Bright pink, biconvex, oval film-coated tablets

Package unit

60 tablets/PTP - 60 tablets/PTP [10 tablets/PTP packaging x 6]