Rafutan Tablet 10 mg (Rabeprazole)

Adult dosage

Short-term treatment of gastric ulcers: Usually, administer lafutidine 10mg orally twice daily, in the morning and before bedtime. In clinical trials of up to 8 weeks, most ulcers healed within 8 weeks, although healing time may vary occasionally. Short-term treatment of duodenal ulcers: Usually, administer lafutidine 10mg orally twice daily, in the morning and before bedtime. In clinical trials of up to 6 weeks, most ulcers healed within 6 weeks, although healing time may vary occasionally. Improvement of gastric mucosal lesions in acute and chronic gastritis: Usually, administer lafutidine 10mg orally once daily before bedtime. In clinical trials of up to 2 weeks, most lesions healed within 2 weeks, although healing time may vary occasionally. Combination antibiotic therapy for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. Preanesthetic medication: Usually, administer lafutidine 10mg orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). Treatment of reflux esophagitis: Administer lafutidine 10mg orally twice daily.

This medication should not be used in patients with hypersensitivity to specific components. Additionally, as this medication contains lactose, patients with hereditary issues such as galactose intolerance, lactase deficiency, and glucose-galactose malabsorption should avoid taking it. Patients with allergies or hypersensitivity to soybean oil, soy, peanuts, etc., should also avoid using this medication as a precaution. Patients with a history of drug hypersensitivity, or issues with liver or kidney function, patients undergoing dialysis, elderly patients, and patients with lipid metabolism disorders should take this medication cautiously. This medication can cause severe allergic reactions such as anaphylaxis; therefore, if symptoms like facial pallor, low blood pressure, or difficulty breathing appear, the medication should be stopped immediately and medical personnel should be informed. Liver function impairment or jaundice symptoms may occur, so regular liver function tests are necessary, and use should be stopped if abnormalities are found. If symptoms of decreased blood cell count occur, such as throat pain, fatigue, fever, etc., medication should be stopped immediately. Rarely, serious side effects such as skin rash, convulsions, and heart conduction abnormalities have been reported, so medical consultation is advised if any unusual symptoms arise. Gastrointestinal symptoms such as constipation, diarrhea, nausea, vomiting, abdominal bloating, and loss of appetite may occur. Central nervous system symptoms such as headache, insomnia, drowsiness, confusion, hallucinations, altered consciousness, and dizziness may appear. During this time, symptoms such as chills, heat sensation, facial flushing may be reported in the circulatory system, and in the blood count, there may be an increase or decrease in white blood cells, or a decrease in red blood cells. Regular testing is important as various elevations in liver and kidney function tests may be observed. Clinical trials have relatively frequently reported gastrointestinal symptoms and liver function abnormalities, but serious adverse reactions were rare. If malignancy is suspected, this medication may alleviate symptoms and delay diagnosis; thus, if warning symptoms like weight loss, recurrent vomiting, or hematemesis occur, it is essential to undergo examination. If malignancy of the stomach is confirmed following initial examination, the use of this medication should be discontinued. During treatment, the patient's condition should be closely monitored, and the minimal effective dose should be used; if no effect is observed, alternative treatments should be considered. Especially for patients at risk of excessive fat overload, plasma lipid levels should be monitored, and dosing adjusted as necessary. Elderly patients should be cautious with dosage and administration intervals due to reduced physical function. Dialysis patients may experience elevated blood concentrations, so treatment should start with low doses and be administered cautiously. Pregnant women should take this medication only when the benefits outweigh the risks as determined by their physician, and breastfeeding women are advised not to use this medication as it may be secreted in breast milk. The safety of this medication in children has not been established, so caution is required for use. This medication should be stored out of the reach of children and kept in its original container to prevent misuse or deterioration of quality.

• Shock
• symptoms of anaphylaxis
• facial pallor
• hypotension
• generalized rash
• dyspnea
• hepatic dysfunction
• jaundice
• agranulocytosis
• pharyngitis

This medication should be stored in a tightly closed container, protected from air and moisture, at room temperature between 1 to 30 degrees Celsius. Storing it this way can help maintain its effectiveness.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle