Question 1

What are the indications and effects of Selparin Tablet 1 mg (Rasagiline Mesylate)?

Accepted Answer

This medication is used for the treatment of idiopathic Parkinson's disease. Initially, it is taken alone or in conjunction with dopaminergic agonists to alleviate symptoms. Additionally, it can be used with levodopa in patients experiencing motor fluctuation symptoms, especially during 'end of dose fluctuation,' to improve motor symptoms in patients with Parkinson's disease and enhance their quality of life.

Question 2

What are the dosage and administration instructions for Selparin Tablet 1 mg (Rasagiline Mesylate)?

Accepted Answer

For adults, administer orally once daily as monotherapy or adjunctive therapy.
1) Monotherapy or adjunctive therapy with a dopamine agonist: Administer 1mg orally once daily.
2) Adjunctive therapy with levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If well tolerated and the clinical response is insufficient, the dose may be increased to 1mg once daily.
This medicine may be taken with or without food.

Question 3

What are the side effects of Selparin Tablet 1 mg (Rasagiline Mesylate)?

Accepted Answer

Influenza, skin cancer, leukopenia, allergy, decreased appetite, depression, hallucination, headache, cerebrovascular accident, conjunctivitis, dizziness, angina, myocardial infarction, rhinitis, abdominal distention, dermatitis, vesicular rash, musculoskeletal pain, cervical pain, arthritis, urgency, fever, fatigue, peripheral edema, falls, arthralgia, low back pain, cough, insomnia, upper respiratory tract infection, nausea, constipation, vomiting, dry mouth, diarrhea, abdominal pain, dyspepsia, hernia, infection, gingivitis, accidental injury, weight loss, tendinitis, movement disorder, drowsiness, sensory disturbances, ataxia, muscle tone abnormalities, myasthenia, anorexia, abnormal dreams, respiratory distress, rash, hyperhidrosis, orthostatic hypotension, petechiae, bleeding, melanoma, confusion, carpal tunnel syndrome, balance disorder, hallucination, hypertension, pathological gambling, increased libido, hypersexuality, compulsive spending or buying, binge eating, obsessive eating, hypotension, excessive drowsiness, acute renal failure, spinal fracture, rib fracture, tendon injury, pelvic fracture, leg fracture, upper extremity fracture, back pain, knee joint replacement, herniated disc, hypoglycemia, weight loss, dysuria, orthostatic hypotension, malignant hyperthermia, generalized weakness, pulmonary tuberculosis, hallucination, semi-consciousness, gait disturbance, ocular movement seizure, facial paralysis, spinal canal stenosis, worsening of Parkinson's disease, subdural hematoma, pneumonia, myalgia, osteoporosis, limb weakness, unspecified contusion, scoliosis, thirst, hematuria, frequent urination, vaginitis, conjunctival hyperemia, diplopia, visual impairment, skin hypertrophy, palpitations, arrhythmia, gastrointestinal discomfort, gas reflux, excessive salivation, increased bowel movements, unspecified gastrointestinal disease, hyperacidity, gastroesophageal reflux, gastric irritation, gastrointestinal motility disorders, periodontitis, Helicobacter pylori gastritis, anemia, leg pain, chest pain, syncope, periorbital edema, facial flushing, pain, delirium, sleep disorder, aggression, amnesia, memory impairment, lethargy, sleepwalking, psychosexual disorder, skin tingling, tremor, freezing phenomenon, limb tremor, focal muscle spasm syndrome, leg cramps, polyuria, tremor, stuttering, speech disorder, language disorder, localized inflammation, itching, urticaria, eyelid skin disease, boil, hair loss, contusion, abnormal sputum, increased sputum, cold, bronchitis

Question 4

What precautions should be taken when using Selparin Tablet 1 mg (Rasagiline Mesylate)?

Accepted Answer

This medicine should not be used by patients who are allergic to this medicine's active ingredient or other components.

Patients currently taking or who have recently stopped other MAO inhibitors or certain medications (such as pethidine, tramadol, dextromethorphan) should not take this medicine.

Patients with moderate to severe liver dysfunction should not use this medicine, and mild liver impairment should use it with caution.

During treatment with this medicine, various side effects such as flu, dermatitis, headache, dizziness, depression, hallucinations, conjunctivitis, rhinitis, and musculoskeletal pain may occur.

Especially in patients with Parkinson's disease, caution is required as hallucinations, confusion, and abnormal motor symptoms may occur.

This medicine may cause drowsiness or sudden sleep episodes when taken with dopaminergic therapies, so caution is needed when driving or operating hazardous machinery.

Additionally, this medication may interact with certain drugs; therefore, patients should consult their physician or pharmacist if they are taking other medications.

Pregnant or breastfeeding women should use this medicine with caution, and safety and efficacy in children under 18 years have not been established.

In case of overdose, serious side effects may occur, requiring immediate medical attention, as no specific antidote exists; symptomatic treatment should be provided based on the symptoms.

Finally, this medicine should be stored out of reach of children, protected from direct sunlight, and stored at a temperature between 1 and 25 degrees Celsius.

Selparin Tablet 1 mg (Rasagiline Mesylate)

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