Napudy Tablet (Lafutidine)

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dose is lafutidine 10mg orally twice daily, in the morning and at bedtime. In clinical trials with treatment for up to 8 weeks, most ulcers healed within 8 weeks; however, healing time may occasionally vary among patients. 2. Short-term treatment of duodenal ulcers: The usual dose is lafutidine 10mg orally twice daily, in the morning and at bedtime. In clinical trials with treatment for up to 6 weeks, most ulcers healed within 6 weeks; however, healing time may occasionally vary among patients. 3. Improvement of gastric mucosal lesions in acute gastritis and chronic gastritis: The usual dose is lafutidine 10mg orally once daily at bedtime. In clinical trials with treatment for up to 2 weeks, most lesions healed within 2 weeks; however, healing time may occasionally vary among patients. 4. Combination therapy with antibiotics for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is lafutidine 10mg per dose, given twice orally (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer lafutidine 10mg per dose twice orally.

This medication should not be used in patients with a history of allergy to any of its components. This medication contains lactose; therefore, individuals with genetic conditions such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption should not take it. Patients with a history of allergic reactions to medications, those with impaired liver or kidney function, patients undergoing dialysis, and the elderly should exercise caution when using this medication. This medication can occasionally cause severe allergic reactions; if symptoms such as pallor, decreased blood pressure, red spots on the body, or difficulty breathing occur, stop taking the medication immediately and seek medical attention. Liver function abnormalities or jaundice symptoms may occur, so regular liver function tests are recommended, and if abnormalities are found, discontinue this medication. Severe hematological abnormalities such as agranulocytosis or thrombocytopenia may develop, prompting immediate notification of healthcare professionals if symptoms like pharyngitis, fatigue, or fever arise. Other serious adverse effects such as rare skin rashes, seizures, or cardiac rhythm disturbances have been reported; thus, any unusual symptoms should warrant immediate consultation with a specialist. Gastrointestinal symptoms may include constipation, diarrhea, nausea, vomiting, abdominal bloating, and loss of appetite, while central nervous system symptoms may include headache, insomnia, and drowsiness. The elderly may have reduced physical function, so it is necessary to adjust dosage and intervals while closely monitoring their condition. Dialysis patients may require careful dosing starting at low doses due to the potential for increased blood concentration of this medication. Pregnant women or those who could become pregnant should only take this medication if the physician determines that the benefits outweigh the risks; breastfeeding women are advised not to take this medication since it may be excreted in breast milk. Safety in children has not been established, and it is advisable not to use this medication in pediatric patients. This medication should be stored out of reach of children and in its original container to prevent misuse or degradation of quality. This medication may conceal symptoms of malignant tumors or delay diagnosis, so patients with or suspected of having gastric ulcers should verify the presence of malignancy. If there is no improvement during treatment, switching to an alternative therapy may be necessary, and regular monitoring of blood, liver, and kidney function is required.

• Shock
• symptoms of anaphylaxis
• pallor
• hypotension
• systemic rash
• dyspnea
• liver dysfunction
• jaundice
• agranulocytosis
• pharyngitis

This medication may be sensitive to air or moisture; therefore, it should be stored in a tightly sealed container. It is advisable to maintain the storage temperature between 1 and 30 degrees Celsius to preserve the medication's efficacy and safety for a long time.

Appearance

White, round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle