Mao Rex Tablet 1 mg (Rasagiline Mesylate)

Adult dose

This medicine is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy with a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy with levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If well tolerated and the clinical response is inadequate, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

This medicine should not be administered to certain patients. First, patients with an allergic reaction to the main component of this drug or to any other components should not take it. In addition, patients who are currently taking or have stopped taking other MAO inhibitors within the last two weeks may be at risk if they use this drug. Patients who are currently taking or have recently stopped specific medications such as pethidine, tramadol, or dextromethorphan should also avoid this drug. This medication is not to be administered to patients with moderate to severe liver impairment. When taking this drug, various side effects may occur. Commonly reported symptoms include headache, dizziness, nausea, insomnia, arthralgia, fever, and fatigue. Additionally, mental symptoms such as depression or hallucinations may also occur, so caution is required. Rarely, cardiovascular anomalies such as myocardial infarction or angina can also be observed. Occasionally, a hypertensive crisis with sudden elevations in blood pressure may occur while taking this medication, so it is essential to monitor blood pressure. Furthermore, when taken with dopamine treatments, drowsiness or sudden sleep may occur, hence special caution is advised when driving or operating machinery. This medication interacts severely with specific drugs, so coadministration should be approached with caution. In particular, taking it with other MAO inhibitors, pethidine, tramadol, dextromethorphan, or antidepressants can lead to severe side effects. Additionally, the coadministration with sympathomimetics or certain cold medications is also not recommended. Women who are pregnant or breastfeeding should be careful when using this drug, and its safety in children under 18 years has not been established. Elderly persons over 65 do not require special dosage adjustments. In cases of overdose with this medication, serious symptoms such as hypertensive crisis or serotonin syndrome may appear, so immediate medical attention should be sought, and there is no specific antidote available, thus treatment should be symptomatic. Lastly, this medication should be stored out of reach of children and at a temperature between 1-25 degrees Celsius, and transferring it to another container should be avoided.

• Influenza
• skin cancer
• leukopenia
• allergy
• decreased appetite
• depression
• hallucinations
• headache
• cerebrovascular accident
• conjunctivitis

This medication should be stored in a tightly closed container to prevent air and moisture from entering. It is advisable to maintain the storage temperature between 1 degree and 30 degrees Celsius.

Appearance

Flat round tablets with white edges

Package unit

30 tablets/PTP [10 tablets/PTP x 3]