Medication info
Hanwha Rasagiline Tablets 1 mg (Rasagiline Mesylate)

Hanwha Rasagiline Tablets 1 mg (Rasagiline Mesylate)

Prescription medicationTabletOral
Ingredient · strength
Rasagiline Mesylate›1.56mg / 1 tablet
Manufacturer / importer
Hanwha Pharmaceutical Co., Ltd.
Appearance
White round tablets
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 201908457 · Approved 2019.12.17

Summary

Main use
Treatment of idiopathic Parkinson's disease
Who takes it
Adults
Adult dose
This medicine is administered orally once daily to adults as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy with a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy with levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If well tolerated and an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Ingredients

Manufacturer
Hanwha Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of idiopathic Parkinson's disease

  • Idiopathic Parkinson's disease
  • motor fluctuations
View approved original text

This medication is used for patients with idiopathic Parkinson's disease. Initially, it may be used alone or as an adjunct therapy along with dopaminergic agents. It is also prescribed to patients experiencing 'end of dose fluctuations,' to supplement their levodopa treatment. This helps to effectively manage various symptoms of Parkinson's disease and improve the quality of life.

How to take

Adult dose

This medicine is administered orally once daily to adults as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy with a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy with levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If well tolerated and an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Precautions

This medication should not be taken by individuals who are hypersensitive to certain ingredients. It can be dangerous to use this medication if you are currently taking other MAO inhibitors or certain herbal medicines, or if you have discontinued them within the last 2 weeks. Additionally, co-administration of certain analgesics, cough medications, and some psychiatric medications should be avoided. This medication is not to be administered to patients with moderate to severe hepatic impairment. Various side effects such as headache, dizziness, nausea, insomnia, and arthralgia may occur, so caution is advised. Especially in Parkinson's patients, symptoms such as hallucinations, confusion, and movement disorders may develop, necessitating regular monitoring. This medication may affect blood pressure, so caution is advised for those with symptoms of hypertension or hypotension. Women who are pregnant or breastfeeding should be cautious when using this medication, and safety in pediatric patients has not been established. While taking this medication, it is important to be cautious about drowsiness or sudden sleep occurrences when driving or operating dangerous machinery. Overdosing on this medication may lead to severe side effects, so the dosage must be strictly adhered to. Furthermore, this medication may interact with multiple drugs, so be sure to consult with a doctor or pharmacist if you are taking other medications. It is crucial to store this medication out of the reach of children and keep it at an appropriate temperature.

Side effects

  • Influenza
  • skin cancer
  • leukopenia
  • allergy
  • loss of appetite
  • depression
  • hallucination
  • headache
  • cerebrovascular accident
  • conjunctivitis
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  • dizziness
  • angina
  • myocardial infarction
  • rhinitis
  • abdominal distension
  • dermatitis
  • vesicular rash
  • musculoskeletal pain
  • cervical pain
  • arthritis
  • urinary urgency
  • fever
  • lethargy
  • peripheral edema
  • falls
  • arthralgia
  • low back pain
  • cough
  • insomnia
  • upper respiratory infection
  • orthostatic hypotension
  • nausea
  • constipation
  • vomiting
  • dry mouth
  • diarrhea
  • abdominal pain
  • dyspepsia
  • hernia
  • infection
  • gingivitis
  • accidental injury
  • weight loss
  • tendinitis
  • movement disorders
  • drowsiness
  • sensory disturbances
  • ataxia
  • muscle hypertonia
  • myasthenia
  • anorexia
  • abnormal dreams
  • respiratory distress
  • rash
  • hyperhidrosis
  • petechiae
  • hemorrhage
  • melanoma
  • confusion
  • carpal tunnel syndrome
  • balance disorders
  • hypotension
  • pathological gambling
  • increased libido
  • hypersexuality
  • compulsive spending or buying
  • binge eating
  • compulsive eating
  • excessive drowsiness
  • acute renal failure
  • malignant hyperthermia
  • systemic weakness
  • pulmonary tuberculosis
  • semicoma
  • gait disturbance
  • ocular motor seizures
  • facial paralysis
  • spinal canal stenosis
  • exacerbation of Parkinson's disease
  • subdural hemorrhage
  • pneumonia
  • spinal fracture
  • rib fracture
  • tendon injury
  • pelvic fracture
  • leg fracture
  • upper limb fracture
  • low back pain
  • knee arthroplasty
  • intervertebral disc herniation
  • hypoglycemia
  • weight loss
  • dysuria
  • hematuria
  • frequency of urination
  • insufficient urine volume
  • nocturia
  • urinary incontinence
  • vaginitis
  • conjunctival injection
  • diplopia
  • visual impairment
  • skin hypertrophy
  • palpitations
  • arrhythmia
  • gastrointestinal discomfort
  • retrograde gas
  • hypersecretion of saliva
  • irritable bowel syndrome
  • fissured tongue
  • increased frequency of bowel movements
  • unspecified intestinal disease
  • esophagitis
  • excessive gastric acid
  • gastroesophageal reflux
  • gastric irritation
  • gastroenteritis
  • intestinal motility disorder
  • periodontitis
  • Helicobacter pylori gastritis
  • anemia
  • leg pain
  • chest pain
  • syncope
  • periorbital edema
  • facial flushing
  • pain
  • hallucination
  • sleep disorder
  • aggression
  • amnesia
  • memory impairment
  • lethargy
  • sleep talking
  • psychosexual disorder
  • skin paresthesia
  • tremor
  • freezing phenomenon
  • limb tremors
  • tic disorder
  • leg cramps
  • polyuria
  • tremors
  • stuttering
  • voice disorders
  • speech disorders
  • localized inflammation
  • itching
  • urticaria
  • eyelid skin disease
  • boil
  • hair loss
  • contusion
  • abnormal sputum
  • increased sputum
  • cold
  • bronchitis
  • heartburn
  • systemic weakness
  • worsened tremor

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container as it may deteriorate when exposed to air or light. It is important to maintain a storage temperature between 1 to 25 degrees Celsius at room temperature.

Appearance and packaging

Appearance

White round tablets

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.