Roputine Tablet 10mg (Rabeprazole)

Adult dose

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine per dose, administered orally twice daily in the morning and at bedtime. Clinical trials in which treatment was administered for up to 8 weeks showed that most ulcers healed within 8 weeks, although the healing period may occasionally vary among patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine per dose, administered orally twice daily in the morning and at bedtime. Clinical trials in which treatment was administered for up to 6 weeks showed that most ulcers healed within 6 weeks, although the healing period may occasionally vary among patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily at bedtime. Clinical trials in which treatment was administered for up to 2 weeks showed that most lesions healed within 2 weeks, although the healing period may occasionally vary among patients. 4. Combination therapy with antibiotics for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 days or 14 days. 5. Premedication before anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (at bedtime on the day before surgery and 2 hours before administration of anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine per dose orally twice daily.

This medication should not be used in patients who are allergic to its components. It also contains lactose; therefore, patients with genetic issues such as galactose intolerance, lactase deficiency, or glucose-galactose malabsorption should avoid taking it. Caution is advised when administering to patients with a history of allergic reactions to medication, those with impaired liver or kidney function, patients undergoing dialysis, and elderly patients, and their conditions must be closely monitored. This medication can rarely cause a severe allergic reaction called anaphylactic shock; if symptoms such as facial pallor, hypotension, skin flushing, or breathing difficulties occur after administration, it should be immediately discontinued, and appropriate treatment should be provided. There may be symptoms of liver dysfunction or jaundice, so regular liver function tests should be conducted, and the medication should be discontinued if abnormalities are found. Blood-related adverse symptoms such as agranulocytosis or thrombocytopenia may arise, so if symptoms such as sore throat, general malaise, or fever occur, consult a doctor immediately. This medication has been reported to cause various side effects such as skin rash, seizures, and heart block, so it's vital to notify medical staff if any unusual symptoms occur. Diverse side effects in the gastrointestinal, central nervous, circulatory, blood, liver, and kidney systems have been reported in clinical trials and post-marketing surveys, so careful monitoring is necessary. Patients suspected of having malignant tumors must undergo diagnostic tests before taking this medication, and if malignant gastric cancer is identified, it should be discontinued immediately. During treatment, the progress of the disease should be closely monitored, and if not effective, it is advisable to switch to another treatment method. Elderly patients must be careful with dosing and intervals due to reduced physical functions. Dialysis patients may have increased blood concentration, so it should be started at a low dose and monitored. Pregnant women or women who may become pregnant should take it carefully according to the doctor's judgment, and breastfeeding women should avoid taking it as it may be excreted in breast milk. Safety for children has not been established; therefore, it is preferable not to administer this medication to children. This medication should be kept out of reach of children and stored in its original container to maintain its quality. Carcinogenicity has not been observed in animal experiments; however, hyperplasia of neuroendocrine cells has been reported at high doses, and some side effects appeared in reproductive toxicity tests, although no fetal malformations were observed.

• Shock
• symptoms of anaphylaxis
• pallor
• hypotension
• generalized urticaria
• dyspnea
• liver dysfunction
• jaundice
• agranulocytosis
• pharyngitis

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle