Famotidine Tablet (Famotidine)

Adult dose

1. Gastric ulcer, duodenal ulcer, anastomotic ulcer, upper gastrointestinal bleeding, gastroesophageal reflux disease, Zollinger-Ellison syndrome: As famotidine, take 20 mg orally twice daily (after breakfast, after dinner, or at bedtime) or 40 mg orally once daily (at bedtime). In cases of upper gastrointestinal bleeding, treatment is usually initiated intravenously and switched to oral administration once possible. 2. Acute gastritis, acute exacerbation of chronic gastritis

This medication should not be used by individuals who have had an allergic reaction to its ingredients or to other H2 receptor antagonists. Additionally, since this medication contains lactose, people with lactose intolerance or galactose intolerance, or specific genetic metabolic disorders should not take it. Individuals with a history of drug allergies should use this medication with caution, and those with impaired kidney function may need to reduce the dose or increase the interval between doses due to potential increased drug concentration. Those with heart disease should take care when using this medication due to the risk of cardiovascular side effects, and individuals with poor liver function should also exercise caution as symptoms may worsen. Elderly patients are at a higher risk of decreased kidney function, which could lead to increased drug concentration, so dose adjustment may be necessary. While taking this medication, serious allergic reactions, blood cell reductions, severe adverse reactions on the skin and mucous membranes, liver dysfunction, muscle damage, cardiac arrhythmias, consciousness disorder or seizures, nephritis, and pneumonia may occur rarely; therefore, they should consult a physician immediately if any unusual symptoms arise. Generally, treatment progress should be monitored closely, and only the minimal effective dose should be used; if no effect is observed, alternative treatment should be considered. This medication dissolves in the mouth but is not absorbed through the oral mucosa; therefore, it must be swallowed with water or saliva. Patients undergoing dialysis should be cautious as taking this medication alongside phosphate binders may affect calcium absorption. This medication may have reduced concentration or efficacy when taken with certain antifungals or some anticancer drugs, so it should be reported to a physician. Women who are pregnant or may become pregnant should only take this medication when the benefits outweigh the risks, and breastfeeding individuals are advised to discontinue nursing as the drug may be transmitted through breast milk. Safety in children has not been sufficiently established, and there is limited experience in use, so caution is advised. Finally, this medication may mask symptoms of gastric cancer; therefore, it should only be used after ensuring that there are no malignant diseases.

Serious side effects

Shock, hypersensitivity (anaphylaxis, respiratory distress, generalized erythema, angioedema, urticaria), pancytopenia, agranulocytosis, aplastic anemia, hemolytic anemia, thrombocytopenia, Stevens-Johnson syndrome, Lyell syndrome, liver dysfunction, jaundice, rhabdomyolysis, QT prolongation, ventricular tachycardia, ventricular fibrillation, consciousness disorder, seizures, interstitial nephritis, acute kidney failure, interstitial pneumonia, heart failure

Mild side effects

Rash, pruritus (erythema), facial swelling, blood abnormalities (leukopenia, eosinophilia), constipation, diarrhea, dry mouth, nausea, vomiting, abdominal distension, decreased appetite, stomatitis, increased blood pressure, facial flushing, tinnitus, bradycardia, tachycardia, atrioventricular block, bronchospasm, elevated AST (GOT), ALT (GTP), ALP, increased total bilirubin, LDH, liver dysfunction, headache, drowsiness, insomnia, hallucinations, agitation, excitement, libido increase

This medication should be stored in a tightly closed container to prevent air and moisture exposure, and it is recommended to store it at room temperature between 1 degree and 30 degrees Celsius. Proper storage maintains the effectiveness of the medication for a longer duration.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle