Medication info
Yespra Tablet 20mg (Esomeprazole Magnesium Trihydrate)

Yespra Tablet 20mg (Esomeprazole Magnesium Trihydrate)

Prescription medicationTablet경구 · 정맥
Ingredient · strength
Esomeprazole Magnesium Trihydrate›22.3mg / 1 tablet
Manufacturer / importer
(주)유앤생명과학
Appearance
Pink round film-coated tablet
Packaging
28 tablets/PTP[((14 tablets/PTP) X 2)]
Approval status
Active

MFDS item code 201908380 · Approved 2019.12.12

Summary

Main use
Treatment of gastroesophageal reflux disease (including erosive esophagitis) and treatment of peptic ulcers caused by Helicobacter pylori, with preventive effects on gastric and duodenal ulcers.
Who uses it
Adults · Children
Adult dosage
This medication should be swallowed with liquid such as water and should not be chewed or crushed. 1. Gastroesophageal Reflux Disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks. If symptoms persist, continue for 4 more weeks. - Long-term maintenance therapy to prevent recurrence in esophagitis patients: 20 mg once daily. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: 1
Children's dosage
Adolescents aged 12 and older 1. Gastroesophageal Reflux Disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks - If symptoms persist, continue for 4 weeks more - For reflux disease without esophagitis

Ingredients

Manufacturer
(주)유앤생명과학

Efficacy & effects

Treatment of gastroesophageal reflux disease (including erosive esophagitis) and treatment of peptic ulcers caused by Helicobacter pylori, with preventive effects on gastric and duodenal ulcers.

  • Gastroesophageal reflux disease
  • erosive esophagitis
  • esophagitis
  • duodenal ulcer
  • peptic ulcer
  • upper gastrointestinal pain
  • upper gastrointestinal discomfort
  • upper gastrointestinal burning sensation
  • gastric ulcer
  • duodenal ulcer
  • Zollinger-Ellison syndrome
  • rebleeding from gastric ulcers
View approved original text

This medication is used for the treatment of gastroesophageal reflux disease, particularly erosive esophagitis, and for maintenance therapy to prevent the recurrence of esophagitis. It also helps in the treatment and prevention of recurrence of duodenal ulcers and peptic ulcers related to antibiotic therapy for the eradication of Helicobacter pylori. It is effective in treating upper gastrointestinal symptoms associated with the use of non-steroidal anti-inflammatory drugs (NSAIDs) and in the treatment and prevention of gastric ulcers. It is used for the treatment of Zollinger-Ellison syndrome and for maintenance therapy after the prevention of rebleeding due to gastric or duodenal ulcers. Thus, it improves symptom relief and prevention of recurrence for various gastrointestinal diseases.

Dosage and Administration

Adult dosage

This medication should be swallowed with liquid such as water and should not be chewed or crushed. 1. Gastroesophageal Reflux Disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks. If symptoms persist, continue for 4 more weeks. - Long-term maintenance therapy to prevent recurrence in esophagitis patients: 20 mg once daily. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: 1

Children's dosage

Adolescents aged 12 and older 1. Gastroesophageal Reflux Disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks - If symptoms persist, continue for 4 weeks more - For reflux disease without esophagitis

Precautions

This medication should not be used in patients with allergies to specific components or who have had hypersensitivity reactions. Additionally, it is unsafe for patients taking certain antibiotics or antivirals, women with a history of myocardial infarction, or those who are breastfeeding. Patients allergic to the dye Yellow No. 4 should use this medication cautiously. While using this medication, caution is needed as blood-related adverse reactions such as leukopenia, thrombocytopenia, and hypomagnesemia may occur. Gastrointestinal symptoms such as headache, dizziness, abdominal pain, diarrhea, and vomiting may also occur, so if symptoms are severe, consultation with a physician is recommended. This medication suppresses gastric acid secretion, which can increase bacterial growth in the stomach, potentially raising the risk of infection. Long-term use may increase the risk of fractures, so attention to bone health is necessary. Regular blood tests and magnesium level checks are recommended for those taking this medication long-term. Due to potential interactions with other medications, especially anticoagulants, anticonvulsants, and antidepressants, it is important to inform healthcare professionals and monitor the condition closely. Caution is needed when using this medication during pregnancy, and it is safest not to take this medication while breastfeeding. In case of overdose, there is no specific antidote, so appropriate treatment should be provided based on symptoms. Keep out of reach of children and store in the original packaging to maintain quality.

Side effects and when to seek care immediately

Serious side effects

Urticaria, angioedema, anaphylaxis, shock, severe rash with fever, blistering, peeling skin, pain in oral/ocular mucosa, shortness of breath, bronchospasm, asthma attack, jaundice (yellowing of the liver), hepatitis, liver failure, sudden and severe headache, seizures, confusion, vision disturbances, paralysis, markedly reduced urine output, severe generalized edema, hypertension, skin and mucosal syndrome (Stevens-Johnson syndrome),

Mild side effects

Headache, dizziness, paresthesia, drowsiness, taste disturbance, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal distension, nausea, vomiting, dry mouth, stomatitis, increased liver enzymes, hepatitis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, muscle weakness, interstitial nephritis, gynecomastia, asthenia, increased sweating, Clostridium difficile infection-related diarrhea, abdominal distension, allergic reactions, back pain, chest pain, sternum pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture. It is recommended to store at room temperature between 1°C and 30°C.

Appearance and packaging

Appearance

Pink round film-coated tablet

Package unit

28 tablets/PTP[((14 tablets/PTP) X 2)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

Related searches

Search tags

Suggested searches

This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.