Medication info
Yes-Pra Tablet 40 mg (Esomeprazole Magnesium Trihydrate)

Yes-Pra Tablet 40 mg (Esomeprazole Magnesium Trihydrate)

Prescription medicationTablet경구 · 정맥
Ingredient · strength
Esomeprazole Magnesium Trihydrate›44.5mg / 1 tablet
Manufacturer / importer
(주)유앤생명과학
Appearance
Pink round film-coated tablet
Packaging
28 tablets/PTP[((14 tablets/PTP) X 2)]
Approval status
Active

MFDS item code 201908379 · Approved 2019.12.12

Summary

Main use
Improvement of gastrointestinal diseases such as treatment of gastroesophageal reflux disease (erosive reflux esophagitis) and prevention of recurrence of Helicobacter pylori-positive peptic ulcers.
Who uses it
Adults · Children
Adult dosage
This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: Administer 40 mg once daily for 4 weeks. May continue for an additional 4 weeks if necessary. - Maintenance therapy to prevent recurrence: 20 mg once daily. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: 20 mg once daily, and if symptoms are not controlled after 4 weeks, further medical attention is needed. -
Children's dosage
Adolescents aged 12 and older - Treatment of gastroesophageal reflux disease: For erosive reflux esophagitis treatment, administer 40 mg once daily for 4 weeks and may continue for an additional 4 weeks if necessary. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis:

Ingredients

Manufacturer
(주)유앤생명과학

Efficacy & effects

Improvement of gastrointestinal diseases such as treatment of gastroesophageal reflux disease (erosive reflux esophagitis) and prevention of recurrence of Helicobacter pylori-positive peptic ulcers.

  • Gastroesophageal reflux disease
  • erosive reflux esophagitis
  • esophagitis
  • duodenal ulcers
  • peptic ulcers
  • upper gastrointestinal pain
  • upper gastrointestinal discomfort
  • upper gastrointestinal burning sensation
  • gastric ulcers
  • duodenal ulcers
  • Zollinger-Ellison syndrome
  • gastric ulcer rebleeding
View approved original text

This medication is used to treat gastroesophageal reflux disease and erosive reflux esophagitis, and it is also suitable for long-term maintenance therapy to prevent recurrence. It is effective in combination with antibiotics for the treatment of duodenal ulcers and peptic ulcers associated with Helicobacter pylori infection. It also helps to treat and prevent upper gastrointestinal symptoms, gastric ulcers, and duodenal ulcers due to non-steroidal anti-inflammatory drug use. It is used in the treatment of Zollinger-Ellison syndrome and for maintenance therapy to prevent rebleeding of gastric and duodenal ulcers induced by intravenous injection. This drug is effective for the treatment and prevention of various gastrointestinal diseases.

Dosage and Administration

Adult dosage

This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: Administer 40 mg once daily for 4 weeks. May continue for an additional 4 weeks if necessary. - Maintenance therapy to prevent recurrence: 20 mg once daily. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: 20 mg once daily, and if symptoms are not controlled after 4 weeks, further medical attention is needed. -

Children's dosage

Adolescents aged 12 and older - Treatment of gastroesophageal reflux disease: For erosive reflux esophagitis treatment, administer 40 mg once daily for 4 weeks and may continue for an additional 4 weeks if necessary. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis:

Precautions

This medication should not be used in certain patients. For example, patients with allergies to this medication, its components, or benzimidazole derivatives, patients allergic to penicillin or macrolide antibiotics, patients taking specific cardiac medications, patients with a history of myocardial infarction, and breastfeeding women should not take this medication. This medication may cause various side effects. Commonly, headaches, abdominal pain, diarrhea, constipation, nausea, and vomiting may occur, and rarely, blood abnormalities, allergic reactions, hypomagnesemia, mental confusion, liver dysfunction, skin rashes, myalgia, and nephritis have been reported. Particularly, long-term use may increase the risk of hypomagnesemia and fractures, so caution is required. As this medication inhibits gastric acid secretion, it may slightly increase the risk of certain bacterial infections due to lower gastric acidity. Hospitalized patients may have a higher risk of diarrhea caused by Clostridium difficile, so if diarrhea persists, consult a doctor immediately. Regular check-ups and consultations with a doctor are necessary if this medication is taken for a prolonged period. Especially, if taken for more than one year, monitoring for decreased bone density or the development of gastric polyps should be done according to healthcare provider guidance. This medication may interact with other drugs, so inform healthcare providers of any medications currently being taken. Caution is especially needed when used together with anticoagulants, antiviral agents, certain antibiotics, anticonvulsants, and antidepressants. Data on the safety of this medication during pregnancy is limited, so pregnant women should definitely consult a doctor before taking it. Additionally, it is advisable for breastfeeding women to avoid using this medication. In case of overdose, there are no specific antidotes, so it is important to receive appropriate treatment based on symptoms, and it should be kept out of reach of children. Transferring the medication to a different container is not advisable as it may affect quality.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema, anaphylaxis, shock, severe hypomagnesemia, mental confusion, pancreatitis, jaundice, liver failure, skin and mucous membrane syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), interstitial nephritis, very severe headache, seizures, altered consciousness, deep vein thrombosis (ventricular tachycardia, ventricular fibrillation, torsades de pointes)

Mild side effects

Headache, dizziness, paresthesia, drowsiness, taste disturbance, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, elevated liver enzymes, hepatitis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, muscle weakness, asthenia, increased sweating, Clostridium difficile-associated diarrhea, allergic reactions, facial edema, facial flushing, fatigue, fever, and more.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to protect it from air or moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature.

Appearance and packaging

Appearance

Pink round film-coated tablet

Package unit

28 tablets/PTP[((14 tablets/PTP) X 2)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.