Viewing nowAntoone Capsule (Dried Grape Leaf Extract)
Vitis Vinifera Leaf Dried Extract 180mg
Hard capsule · OTC medication
Hana Pharmaceutical Co., Ltd.

MFDS item code 201908354 · Notified 2019.12.11 · Insurance code 657806960
Improvement of symptoms of chronic venous insufficiency (such as lower-limb edema and heaviness)
This medication is used to improve leg swelling, pressure sensation, and pain caused by chronic venous insufficiency.
Adults: Take 360 mg of dried grape leaf extract once daily with water before breakfast.
This medication should not be taken by individuals who are allergic to it or any of its components. Additionally, children and adolescents should not take this medication. Individuals with glucose-galactose malabsorption should particularly avoid this capsule form of the medication. It is advisable for pregnant women or women who may become pregnant not to take this medication. Women who are breastfeeding should also avoid taking this medication, as it is uncertain whether it passes into breast milk; it is recommended to either avoid taking this medication or discontinue breastfeeding. Women who may become pregnant should consult with a doctor or pharmacist before taking this medication. If any allergy symptoms, skin rashes, hives, itching, or photosensitive skin reactions occur while taking this medication, discontinue use immediately and consult a healthcare professional. Also, gastrointestinal symptoms such as abdominal pain, nausea, diarrhea, or rarely headaches may occur; consult a professional if these symptoms persist. If any unusual symptoms such as sudden pain, swelling, skin discoloration, tension, or warmth occur in one leg, it may indicate serious thrombosis, and a doctor should be notified immediately. If symptoms do not improve after taking the medication for six weeks, discontinue use and consult a doctor for other possible causes. This medication may require several weeks of use for effectiveness; however, it should not be taken for more than three months. The effects on driving or operating machinery are not clearly known, so caution is advised. No serious side effects have been reported from overdose, but it is important to adhere to the prescribed dosage. Treatments such as leg bandages, compression stockings, and washing with cold water prescribed by a doctor should continue regardless of this medication. This medication should be stored out of reach of children, protected from direct sunlight, and kept in a cool, dry place. Additionally, transferring this medication to another container may lead to misuse or a decrease in quality, so it must be stored in its original container with the cap tightly closed.
Not everyone experiences these, and they can vary from person to person.
This medication may be sensitive to air or moisture, so it must be stored in a tightly closed container. It is important to maintain room temperature, specifically between 1 degree Celsius and 30 degrees Celsius, to safely preserve the medication's effectiveness.
A hard capsule with dark brown upper and lower parts filled with a dark purple powder.
30 capsules/bottle, 300 capsules/bottle
Even with the same ingredient, strength, dosage form and how it is taken can differ.
Viewing nowVitis Vinifera Leaf Dried Extract 180mg
Hard capsule · OTC medication
Hana Pharmaceutical Co., Ltd.

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Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.
QCan I take it after eating in the morning?
Answers 1 · 2026.09.14
For anything that needs medical judgment, consult a doctor or pharmacist.
This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.