Kayrilm Tablets 1/250 mg

Adult dose

This medication is administered 1 to 2 times a day before meals or with meals. Dosage may be adjusted based on each patient's current therapy, efficacy, and tolerability, and appropriate blood glucose monitoring should be conducted. Treatment usually begins at a low dose, and adjustments can be made considering the patient's currently prescribed medications and blood glucose levels. The initial daily dose in clinical trials was Glimiperide/Metformin.

This medication may cause severe lactic acidosis or hypoglycemia; therefore, it should be discontinued and a doctor consulted, especially in cases of rapidly declining renal function. It is also safer to temporarily stop administration in the presence of dehydration symptoms, severe diarrhea, vomiting, or fever. Caution is needed when using it along with other medications that can affect renal function. This medication should not be administered to patients with insulin-dependent diabetes, acute metabolic acidosis, severe liver dysfunction, or during pregnancy and breastfeeding. Elderly patients or those with impaired renal function need dosage adjustments and regular renal function checks. In the early stages of treatment, there is a heightened risk of hypoglycemia, so one should be mindful of irregular meals, excessive exercise, and alcohol consumption. If hypoglycemic symptoms occur, sugar should be consumed immediately. This medication may cause various side effects such as gastrointestinal disturbances, allergic reactions, hematological abnormalities, and vitamin B12 deficiency; if any unusual symptoms occur, the physician should be consulted immediately. It is necessary to regularly check the condition of blood sugar control, and especially during stress situations such as surgery or infection, treatment methods may need to be adjusted. Furthermore, this medication can interact with several other drugs, so patients must inform healthcare personnel if they are taking any other medications. Do not use during pregnancy or breastfeeding, and exercise caution when administering to children or adolescents. In case of overdose, severe hypoglycemia or lactic acidosis may occur, necessitating immediate emergency treatment; dialysis may be effective. Keep this medication out of the reach of children and do not transfer it to another container. Finally, be cautious while driving or operating machinery due to the risk of hypoglycemia and other side effects.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, lactic acidosis, thrombocytopenic purpura, liver abnormalities (liver dysfunction, jaundice), severe allergic reactions, severe skin reactions, severe allergic reactions, cardiac arrest, rectal carcinoma, severe hypoglycemia, encephalopathy, altered consciousness due to hypoglycemia, paralysis, seizures, loss of consciousness, coma, severe edema, worsening renal function.

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal distension
• loss of appetite
• dyspepsia
• constipation
• abdominal pain
• taste disturbance
• visual impairment

Store this medication in a tightly sealed container to prevent air exposure, ideally at a temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the medication's efficacy and prevent deterioration.

Appearance

White rectangular film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle