Kailim Tablet 2/500 Milligrams

Adult dose

This medication is administered 1 to 2 times daily before meals or with meals. The dosage can be adjusted considering the current treatment regimen, effectiveness, and tolerability of each patient, and appropriate blood glucose monitoring should be conducted for this purpose. Typically, treatment is initiated at a low dose, and dosage can be adjusted based on the patient's current medications and blood glucose levels. In clinical trials, the initial dose was glymeperide/metformin hydrochloride 2mg/500mg per day, and based on blood glucose monitoring results, it can be gradually increased up to glymeperide/metformin hydrochloride 8mg/2000mg. While additional effects are rarely seen when administering single-agent glymeperide at doses higher than 4mg per day, some patients have shown better metabolic control when increased to 6mg (or 8mg). When used as an alternative therapy for combination therapy, administration should be based on the current dosing regimen of glymeperide and metformin hydrochloride. Even if a dose was missed, do not exceed the single dose at the next administration.

This medication may accumulate in the body and cause a serious metabolic complication called lactic acidosis if kidney function declines rapidly, so regular monitoring of kidney function is necessary. It is important to temporarily discontinue medication and consult a physician in case of dehydration, severe diarrhea, vomiting, or fever. This medication may increase the risk of death in patients with certain cardiovascular diseases, so caution is advised if there is a history of cardiovascular disease. Pregnant or breastfeeding women should not take this medication, and those planning to become pregnant should consult a physician. There is a risk of hypoglycemia, so be particularly careful with irregular meals, excessive exercise, or alcohol consumption, and take immediate appropriate action if hypoglycemic symptoms appear. Gastrointestinal symptoms (diarrhea, nausea, vomiting, etc.) may occur, but are generally temporary and can be alleviated by taking the medication with meals. Allergic reactions may occur, and if skin abnormalities such as rash or hives appear, inform medical staff immediately. As vitamin B12 deficiency may occur, it is recommended to check vitamin B12 levels through blood tests during prolonged use. The medication may interact with other drugs, so any other medications being taken should be reported to the physician or pharmacist. Blood glucose levels, blood tests, and kidney function tests should be conducted regularly to monitor treatment effects and side effects, and medical staff should be consulted immediately in case of abnormal symptoms. In cases of overdose, serious side effects such as hypoglycemia or lactic acidosis may occur, so strictly adhere to the dosage and seek emergency treatment immediately in case of accidental overdose. Caution is needed while driving or operating machinery due to the risk of accidents from hypoglycemia or dizziness. Store in a safe place out of reach of children, and it is advisable not to transfer to another container.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, drop in blood pressure, severe allergic reaction. Severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, severe skin adverse reactions. Shortness of breath or difficulty breathing, asthma attack, abnormal breathing accompanied by cough and fever. Jaundice (yellowing of the skin or eyes), extreme lethargy, liver abnormalities (jaundice). Severe edema or urinary abnormalities (significantly reduced urine output).

Mild side effects

Diarrhea, nausea, vomiting, abdominal bloating, loss of appetite, indigestion, constipation, abdominal pain, vision impairment related to blood sugar levels, taste disturbance, erythema, itching, rash, hives, thrombocytopenia, leukopenia, hemolytic anemia, erythrocytopenia, agranulocytosis, pancytopenia, vitamin B12 decrease or deficiency, increased liver enzymes, liver function impairment, hepatitis, allergic vasculitis, photosensitivity of the skin, serum sodium.

Store this medication in a tightly sealed container to prevent air and moisture from entering. It is best to maintain the storage temperature between 1 degree and 30 degrees Celsius at room temperature. By storing it this way, the effectiveness of the medication is well preserved, and deterioration can be prevented.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle