Clodrine Tablets (Clopidogrel Sulfate)

Adult dose

1. For patients with ischemic stroke, myocardial infarction, or peripheral arterial disease, take Clopidogrel 75 mg orally once daily. 2. For patients with acute coronary syndrome (unstable angina or non-Q wave myocardial infarction), begin with a loading dose of 300 mg orally once daily on the first day of therapy, followed by a maintenance dose of 75 mg orally once daily. At this time, aspirin 75-325 mg should also be administered once daily. 3. For patients with atrial fibrillation, take 75 mg orally once daily. At this time, aspirin 75-100 mg should also be administered once daily.

This medicine helps blood flow by preventing platelets from aggregating in the blood. Caution is needed as individuals genetically lacking a specific enzyme (CYP2C19) may not respond adequately to this medication. Additionally, it is advisable not to co-administer with medications that activate the CYP2C19 enzyme as this may increase the risk of bleeding. Patients with allergies to this medication, those with bleeding disorders, patients with severe liver damage, breastfeeding women, and those with lactose intolerance should not take this medication. Patients at higher risk for bleeding, those with impaired liver or kidney function, the elderly, underweight patients, and patients with specific allergies should use this medication with caution. If surgery is planned or if there are conditions that pose a bleeding risk, the medication should be discontinued 5 to 7 days before the surgery, and medical personnel should be notified immediately if bleeding symptoms occur. This medication can cause bleeding, and if any bleeding symptoms occur, it is imperative to go to the hospital for blood tests. During the intake of this medication, it is important to consult with a doctor or pharmacist before starting or stopping any new medications, and any bleeding symptoms or adverse reactions should be reported immediately.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral or ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, abnormal respiratory symptoms accompanied by coughing and fever, yellowing of the skin or eyes (jaundice), extreme malaise, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, decreased urine output,

Mild side effects

• Chest pain
• accidental injury
• influenza-like illness
• pain
• fatigue
• edema
• hypertension
• headache
• dizziness
• abdominal pain

This medicine may be sensitive to air and moisture; hence, it should be stored in a tightly closed container. It is also safe to store it at room temperature between 1 and 30 degrees Celsius, avoiding extremely hot or cold places.

Appearance

Pink round film-coated tablets

Package unit

For domestic use - 30 tablets/bottle, For domestic use - 100 tablets/bottle