Famotidine 20 mg Tablets (Famotidine)

Adult dose

For gastric ulcers, duodenal ulcers, anastomotic ulcers, upper gastrointestinal bleeding, gastroesophageal reflux disease, and Zollinger-Ellison syndrome: Famotidine 20 mg is to be administered orally twice daily (after breakfast, after dinner, or at bedtime) or 40 mg once daily (at bedtime). In case of upper gastrointestinal bleeding, treatment should start with injection, and once oral administration becomes possible, it should be switched to oral administration. For acute gastritis, acute exacerbation of chronic gastritis, etc.

This medication should not be used in patients who are allergic to specific components or who are hypersensitive to H2 receptor antagonists. Also, since it contains lactose, it should not be administered to patients with lactose intolerance or certain genetic disorders. Patients with hypersensitivity or problems with the kidneys, liver, or heart should use this drug cautiously, and elderly patients should also take care. This drug can rarely cause serious allergic reactions, blood disorders, skin disorders, liver dysfunction, muscle injury, cardiac arrhythmias, consciousness disorders, kidney problems, pneumonia, and other side effects; therefore, if any abnormal symptoms occur, administration should be immediately discontinued, and medical attention should be sought. Common side effects may include rash, gastrointestinal issues, blood pressure changes, dizziness, and neuropsychiatric symptoms. During treatment, regular blood tests and liver and kidney function tests should be conducted to monitor the condition. This medication dissolves in the mouth but is not absorbed in the oral mucosa; therefore, it must be swallowed with water or saliva. Caution is needed when using this medication in conjunction with phosphate binders in patients undergoing hemodialysis, as efficacy may be reduced. It may interact with other medications, so it is especially important to consult a doctor when taking antifungals or certain antineoplastics. Elderly patients may require dosage adjustments due to decreased kidney function leading to increased drug concentration. Women who are pregnant or may become pregnant should use this medication only if the benefits outweigh the risks, and it is advisable for breastfeeding women to discontinue breastfeeding. The safety of this drug in children has not been sufficiently established, so its use is not recommended. Lastly, this medication may mask symptoms of gastric cancer, so it should be used only after malignancy has been ruled out.

Serious side effects

Shock, hypersensitivity (anaphylaxis, respiratory distress, systemic flushing, angioedema, hives), pancytopenia, agranulocytosis, aplastic anemia, hemolytic anemia, thrombocytopenia, Stevens-Johnson syndrome, Lyell syndrome, liver dysfunction, jaundice, rhabdomyolysis, QT prolongation, ventricular tachycardia, ventricular fibrillation, altered consciousness, seizures, interstitial nephritis, acute renal failure, interstitial pneumonia, and contraction failure.

Mild side effects

• Constipation
• diarrhea or loose stools
• dry mouth
• nausea or vomiting
• abdominal distension
• loss of appetite
• stomatitis
• rash or skin eruptions
• urticaria (erythema)
• facial swelling

This medication should be stored in a tightly closed container to prevent air from entering, and it is recommended to keep it at room temperature between 1 to 30 degrees Celsius. Storing this way will help maintain the drug's effectiveness for a long time.

Appearance

White, round, film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle