Medication info
Memantine Hydrochloride

Memantine Hydrochloride

Prescription medicationTablet경구
Ingredient · strength
Memantine Hydrochloride›10mg / 1 tablet
Manufacturer / importer
삼남제약(주)
Appearance
White rectangular film-coated tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201908159 · Approved 2019.11.29

Summary

Main use
Treatment of moderate to severe Alzheimer's disease
Who takes it
Adults
Adult dose
The maximum daily dose is 20mg, and it should be increased by 5mg weekly over the first 3 weeks. Week 1 (days 1-7): Administer 5mg per day. Week 2 (days 8-14): Administer 10mg per day (5mg twice daily). Week 3 (days 15-21): Administer 15mg per day (10mg in the morning, 5mg in the evening). From week 4 onwards, administer 20mg per day (10mg twice daily). The recommended maintenance dose is

Ingredients

Manufacturer
삼남제약(주)

Efficacy & effects

Treatment of moderate to severe Alzheimer's disease

  • Alzheimer's disease
View approved original text

This medication is used for the treatment of moderate to severe Alzheimer's disease. Alzheimer's disease is a neurodegenerative disorder characterized by a gradual decline in memory and cognitive functions, and this medication helps to relieve symptoms and improve the quality of life for patients.

How to take

Adult dose

The maximum daily dose is 20mg, and it should be increased by 5mg weekly over the first 3 weeks. Week 1 (days 1-7): Administer 5mg per day. Week 2 (days 8-14): Administer 10mg per day (5mg twice daily). Week 3 (days 15-21): Administer 15mg per day (10mg in the morning, 5mg in the evening). From week 4 onwards, administer 20mg per day (10mg twice daily). The recommended maintenance dose is

Precautions

This medication should not be used in patients with allergies to its components or in those with severe liver or kidney dysfunction. It should be administered with caution to patients with epilepsy or those who have a history of seizures, and co-administration with certain medications may worsen side effects, so concomitant use should be avoided. Patients with conditions that may cause changes in urine acidity or those with recent cardiovascular issues should also exercise caution. While taking this medication, side effects such as dizziness, headaches, constipation, drowsiness, and hypertension may occur; if symptoms are severe, consult a physician. There is a potential for drug interactions, particularly with medications affecting the central nervous system, so patients must inform their physician if they are taking any other medications. Women who are pregnant or breastfeeding should consult a physician before taking this medication, and discontinuation of breastfeeding is recommended during treatment. This medication is not recommended for children or adolescents under 18 years of age, as its safety and efficacy have not been established. In case of overdose, symptoms such as confusion, drowsiness, dizziness, hallucinations, and vomiting may appear; immediate medical attention should be sought for appropriate treatment. This medication can affect the central nervous system and impair the ability to drive or operate machinery, so special caution is advised when engaging in these activities during treatment. Finally, store this medication out of the reach of children and do not transfer it to another container for safety.

Side effects and when to seek care immediately

Serious side effects

  • Seizures
  • heart failure
  • venous thrombosis/thromboembolism
  • dyspnea
  • pancreatitis

Mild side effects

  • Dizziness
  • headaches
  • constipation
  • drowsiness
  • hypertension
  • confusion
  • hallucinations
  • psychotic reactions
  • balance disorders
  • gait disturbances
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  • vomiting
  • elevated liver enzyme levels
  • hepatitis
  • fatigue

Not everyone experiences these, and they can vary from person to person.

Storage

This medication can be sensitive to air and moisture, so it must be stored in a tightly sealed container. Additionally, to maintain its effectiveness, it is recommended to store it at a temperature between 1°C and 30°C.

Appearance and packaging

Appearance

White rectangular film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.