Opalost Tablet (Limaprost Alfa-Dex)

Adult dosage

For improvement of ischemic symptoms such as ulcers, pain, and coldness due to thromboangiitis obliterans (Buerger's disease), the usual adult dose is 2 tablets orally three times daily. For improvement of subjective symptoms (lower limb pain and numbness) and walking ability due to acquired lumbar spinal canal stenosis (in patients with a normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet orally three times daily. Adjust the dose as appropriate according to age and symptoms.

This medication should not be used in pregnant women or those who may become pregnant. It contains lactose, so it should not be used in patients with a hereditary problem of lactose intolerance. Patients with a tendency to bleed or those who are taking antiplatelet agents, thrombolytics, or anticoagulants should use this medication with caution. When using this medication, hypersensitivity reactions such as skin rashes or itching may occur, so it should be discontinued immediately if such symptoms arise. Bleeding may rarely occur, so if bleeding symptoms are observed, the medication should be stopped and monitored. Gastrointestinal disorders such as diarrhea, nausea, abdominal discomfort, abdominal pain, loss of appetite, and heartburn may occur, so caution is advised. Liver function abnormalities may occur, so it is advisable to periodically check liver function test results. Rapid heartbeat or, rarely, cyanosis of the extremities or low blood pressure may occur; if such symptoms appear, medical consultation is needed. Symptoms such as headache, facial flushing, dizziness, feeling of heat, fatigue, swelling, breast pain, trembling, excessive hair growth in legs, and anemia may occur. For patients with lumbar spinal canal stenosis, careful observation of symptom changes should guide the decision to continue the use of this medication. The effectiveness of this medication has not been established in severe cases requiring spinal surgery. Safety during pregnancy has not been established, and uterine contraction effects have been reported in animal studies, so it should not be used during pregnancy. Safety in children has not been confirmed, so it is advisable not to use it in children. Elderly patients may have decreased body function; therefore, dosing should be adjusted and used with caution. Administration of a large amount to healthy adults may temporarily lower blood pressure; caution is needed.

• Rash
• itching
• bleeding
• diarrhea
• nausea
• abdominal discomfort
• abdominal pain
• loss of appetite
• heartburn
• vomiting

This medication is susceptible to air and moisture, so it must be stored in a tightly sealed container. It is important to maintain storage temperatures between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's efficacy for a longer period.

Appearance

White round tablet

Package unit

84 tablets/box [21 tablets/blister X 4]