Ezirect Tablet 1.0 mg (Rasagiline Mesylate)

Adult dose

This medication is administered orally once daily to adults as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If well tolerated and an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medication may be taken with or without food.

This drug should not be used in patients who are allergic to the active ingredient or other components of this drug. It should not be administered to patients who are taking other MAO inhibitors or certain natural medicines or have recently discontinued them. In particular, this drug should not be used in patients currently taking or recently stopping medications such as pethidine, tramadol, or dextromethorphan. It is not safe to administer this drug to patients with moderate to severe liver dysfunction. During treatment with this drug, side effects such as flu, skin cancer, leukopenia, allergies, decreased appetite, depression, hallucinations, headaches, conjunctivitis, dizziness, angina, rhinitis, dermatitis, myalgia, arthralgia, urgency, fever, and fatigue may occur. Caution is needed as symptoms such as nausea, dizziness, peripheral edema, falls, cough, and insomnia may appear while taking this medication. Caution is also advised when used with levodopa, as movement disorders or hypotension may occur. While taking this medication, impulsive control disorders may arise, so regular monitoring for abnormal behaviors such as compulsive actions or pathological gambling is necessary. Patients with slight liver dysfunction should also be careful when taking this medication, and it should not be used in those with moderate to severe liver dysfunction. Care must be taken when engaging in risky activities like driving or operating machinery, as this medication may cause drowsiness or sudden sleep occurrences. Numerous drug interactions exist, so particularly avoid concomitant use with MAO inhibitors, pethidine, tramadol, dextromethorphan, antidepressants, and sympathomimetics. Smoking may lower the blood concentration of this medication. Women who are pregnant or breastfeeding should use this medication with caution, as it may affect breastfeeding. This medication should not be used in children under 18 years of age, as its safety and effectiveness have not been established. In cases of overdose, symptoms such as mild mania, hypertensive crises, or serotonin syndrome may develop, necessitating immediate medical attention. This drug should be kept out of reach of children, and storage temperature should be maintained between 1°C and 25°C.

• Influenza
• skin cancer
• leukopenia
• allergy
• appetite loss
• depression
• hallucinations
• headache
• cerebrovascular accident
• conjunctivitis

This drug should be stored in a tightly sealed container to prevent air or moisture ingress, in a cool place at a temperature between 1°C and 25°C. Proper storage will help maintain the effectiveness of the medication and prevent degradation.

Appearance

Flat round tablets with edges that are white or nearly white

Package unit

30 tablets/PTP [(10 tablets/PTP x 3)], 30 tablets/bottle