Exvalset Tablets 5/160mg

Adult dose

The recommended dose of this medication is 1 tablet once daily, taken with water regardless of meals. It is advisable to take it at the same time each day (e.g., in the morning). Consideration can be given to switching to this combination medication if blood pressure is not controlled with monotherapy using amlodipine or valsartan. Dose adjustments and caution are needed for patients with renal impairment, liver impairment, and the elderly.

Child dose

Safety and efficacy have not been established for pediatric patients under 18 years of age; therefore, this medication is not recommended.

This medication can cause serious harm to the fetus and newborn when administered during the second and third trimester of pregnancy; therefore, it should be immediately discontinued upon confirmation of pregnancy. There are patients who should not take this medication. For example, individuals allergic to this medication or other similar medications, pregnant or potentially pregnant women, nursing mothers, and patients with severe renal or liver dysfunction should not take this medication. Additionally, for diabetic patients with moderate to severe renal dysfunction, concomitant use of this medication with certain other drugs may be risky and should be avoided. This medication can cause hypotension in patients with decreased sodium or fluid levels, making it important to verify and supplement this condition before administration. Patients with high potassium levels should also exercise caution, and frequent monitoring of blood potassium levels is required when taken with potassium supplements or potassium-rich medications. Patients with renal vascular issues or those who have had kidney transplants may also be affected in renal function upon administering this medication, requiring careful monitoring. Severe allergic reactions known as angioedema may occur, so if symptoms such as swelling of the face, lips, or tongue appear, the medication should be discontinued immediately. Patients with heart failure or following a myocardial infarction should closely monitor renal function while taking this medication, as hypotension or renal failure may occur in some cases. Caution is advised when driving or operating machinery as dizziness or fatigue may occur. This medication can interact with various other medications, so patients should inform healthcare providers of any other medications they are taking. In cases of overdose, severe hypotension or heart problems may occur, requiring immediate emergency intervention. The safety and effectiveness of this medication in patients under 18 years old have not been established, so it is not recommended for use in this population. For elderly patients, the usual adult dose can be administered, but careful monitoring is required. Regular liver function or renal function tests are recommended during treatment with this medication.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rashes with fever, blisters, skin shedding, oral/ocular mucosal pain, severe dermal reactions, difficulty breathing or shortness of breath, asthma attacks, respiratory issues accompanied by cough and fever, respiratory problems, jaundice (yellowing of the skin or eyes), severe lethargy, liver dysfunction (jaundice), sudden and serious issues.

Mild side effects

• Headache
• dizziness
• drowsiness
• paresthesia
• vertigo
• tinnitus
• tachycardia
• palpitations
• orthostatic hypotension
• hypotension

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is important to maintain storage temperatures between 1 and 30 degrees Celsius. Proper storage will safely preserve the medication's effectiveness.

Appearance

Dark yellow oval film-coated tablets

Package unit

30 tablets/box [10 tablets/PTP X 3]