Candesartan 16 mg (Candesartan Cilexetil)

Adult dose

For essential hypertension, the initial and maintenance doses recommended are 8 to 16 mg of Candesartan Cilexetil administered orally once daily. If blood pressure is not adequately controlled after 4 weeks at a dose of 16 mg once daily, the dose may be increased up to a maximum of 32 mg once daily. For patients with reduced effective blood volume and renal impairment, the initial dose is 4 mg, while patients with liver impairment should start at 2 mg once daily and adjust the dose based on the patient's response.

Child dose

Safety and efficacy have not been established for adolescents and children under the age of 18.

This medication can cause serious harm to the fetus when taken during pregnancy, especially in the second and third trimesters; therefore, it should be discontinued immediately if pregnancy is confirmed. Women who are pregnant or may become pregnant, and nursing mothers should not take this medication. Patients who are allergic to this medication or its components, those with severe liver disease, or hereditary angioedema should not use this medication. Elderly patients, those with hyperkalemia, cirrhosis, heart valve disease, and renal impairment should use this medication with caution, as there is a risk of heart or cerebrovascular issues due to blood pressure lowering. Side effects such as dizziness, back pain, or respiratory infections may occur during treatment; in severe cases, renal function deterioration, hypotension, or hyperkalemia may develop, so regular blood tests and kidney function assessments are important. If blood pressure drops too low or severe side effects occur, consult medical personnel immediately; particularly patients with heart failure may require dosage adjustment and monitoring of their condition. When used in combination with other antihypertensive agents, the blood pressure-lowering effect may increase, so caution is necessary with concurrent use, and when used with potassium-sparing diuretics, there is an increased risk of hyperkalemia, requiring frequent monitoring of blood potassium levels. It is important to inform your doctor before undergoing surgery or anesthesia, as this medication may cause hypotension during the procedure. The safety of this medication in children and adolescents has not been established, so it is not recommended for those under 18 years of age. Caution is advised during driving or operating machinery, as dizziness or drowsiness may occur. In case of overdose, blood pressure may drop significantly, requiring immediate medical attention, and this medication is not removed by dialysis. Store this medication out of reach of children and do not transfer it to another container for safety precautions.

Serious side effects

Hives, angioedema (swelling of the face, lips, tongue, throat, etc.), cold sweat, rash, itching, shortness of breath, kidney damage, acute renal failure, liver abnormalities (jaundice), shock, fainting, loss of consciousness, paralysis, hematuria, hyperkalemia, acute renal failure, liver dysfunction causing jaundice, severe edema, elevated blood pressure, severe allergic reactions, serious neurological symptoms (paralysis), severe skin reactions (severe rash, blisters, skin)

Mild side effects

Dizziness, back pain, respiratory infections (upper respiratory infections, pharyngitis, rhinitis), fatigue, peripheral edema, chest pain, headache, bronchitis, cough, sinusitis, nausea, abdominal pain, diarrhea, vomiting, arthralgia, proteinuria, weakness, fever, paresthesia, indigestion, gastritis, tachycardia, palpitations, increased creatine kinase, hyperglycemia, hypertriglyceridemia, hyperuricemia, myalgia, epistaxis, anxiety, depression, drowsiness, rash, increased sweating, hematuria,

This medication can be sensitive to air and moisture, so it must be stored in a tightly closed container. It is best to maintain a storage temperature between 1°C and 30°C. Storing it this way will help preserve its effectiveness for a longer period.

Appearance

A pale yellow-pink tablet with a convex shape on both sides

Package unit

30 tablets/bottle, 100 tablets/bottle