Medication info
Nexium Tablet 20 mg (Esomeprazole Magnesium Trihydrate)

Nexium Tablet 20 mg (Esomeprazole Magnesium Trihydrate)

Prescription medicationTablet경구 · 정맥
Ingredient · strength
Esomeprazole Magnesium Trihydrate›22.25mg / 1 tablet
Manufacturer / importer
엔비케이제약(주)
Appearance
Pink round film-coated tablet
Packaging
28 tablets/PTP [28 tablets (14 tablets/Alu-Alu X2)]
Approval status
Active

MFDS item code 201907879 · Approved 2019.11.12 · Insurance code 054800560

Summary

Main use
Treatment of gastroesophageal reflux disease (including erosive esophagitis), treatment and prevention of recurrence of Helicobacter pylori positive peptic ulcers, alleviation of gastrointestinal symptoms related to non-steroidal anti-inflammatory drugs, etc.
Who uses it
Adults · Children
Adult dosage
This medication must be swallowed whole and not chewed or crushed with liquids such as water. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks - If treatment fails, an additional 4 weeks of dosing may be considered - Maintenance therapy for prevention of recurrence of esophagitis: 20 mg once daily - Treatment of gastroesophageal reflux disease symptoms without esophagitis: 20 mg once daily
Children's dosage
Adolescents aged 12 and over - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks - If treatment fails, an additional 4 weeks of dosing may be considered - Treatment of gastroesophageal reflux disease symptoms without esophagitis:

Ingredients

Manufacturer
엔비케이제약(주)

Efficacy & effects

Treatment of gastroesophageal reflux disease (including erosive esophagitis), treatment and prevention of recurrence of Helicobacter pylori positive peptic ulcers, alleviation of gastrointestinal symptoms related to non-steroidal anti-inflammatory drugs, etc.

  • Erosive esophagitis
  • esophagitis
  • symptoms of gastroesophageal reflux disease
  • duodenal ulcer
  • peptic ulcer
  • upper gastrointestinal symptoms
  • pain
  • discomfort
  • burning sensation
  • gastric ulcer
  • duodenal ulcer
  • Zollinger-Ellison syndrome
View approved original text

This medication is used for the treatment of gastroesophageal reflux disease, erosive esophagitis, and maintenance therapy for prevention of recurrence. It is also effective for the treatment and prevention of recurrence of duodenal ulcers and peptic ulcers caused by Helicobacter pylori infection. It is indicated for the short-term treatment and prevention of upper gastrointestinal symptoms and gastric ulcers and duodenal ulcers caused by the use of non-steroidal anti-inflammatory drugs. It is beneficial for the treatment and prevention of various gastrointestinal diseases and improvement of the health of the stomach and esophagus.

Dosage and Administration

Adult dosage

This medication must be swallowed whole and not chewed or crushed with liquids such as water. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks - If treatment fails, an additional 4 weeks of dosing may be considered - Maintenance therapy for prevention of recurrence of esophagitis: 20 mg once daily - Treatment of gastroesophageal reflux disease symptoms without esophagitis: 20 mg once daily

Children's dosage

Adolescents aged 12 and over - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks - If treatment fails, an additional 4 weeks of dosing may be considered - Treatment of gastroesophageal reflux disease symptoms without esophagitis:

Precautions

This medication should not be used in patients with known allergies or hypersensitivity to specific components. Additionally, caution is needed when used with certain antibiotics as it may cause hypersensitivity. Women who are breastfeeding or patients with a history of heart disease should also avoid taking this medication. This medication contains lactose, thus lactose-intolerant patients should abstain from taking it. Rarely, various side effects may occur, including blood-related, immune, metabolic, mental, neurological, gastrointestinal, liver, and skin reactions; if any abnormal symptoms occur, consult a physician immediately. Regular monitoring is important during prolonged use. This medication suppresses gastric acid secretion, which may lead to bacterial overgrowth in the stomach and increase the risk of infections. Particularly, high-dose long-term use may increase fracture risk, so caution is required for patients with osteoporosis. Due to many drug interactions, it is essential to inform healthcare personnel of any other medications being taken. Caution is required during pregnancy, and it is safest to avoid taking the medication while breastfeeding. In case of overdose, there is no specific antidote, so appropriate treatment should be based on symptoms. Store this medication out of reach of children and in its original container.

Side effects and when to seek care immediately

Serious side effects

Urticaria, angioedema, anaphylactic reactions, shock, hypomagnesemia, hypocalcemia, hypokalemia, mental confusion, aggression, hallucinations, bronchospasm, microscopic colitis, jaundice, hepatitis, liver failure, encephalopathy, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, Lyell's syndrome, acute generalized exanthematous pustulosis, eosinophilia with systemic symptoms, muscle weakness, allergic interstitial nephritis

Mild side effects

  • Headache
  • dizziness
  • sensory disorders
  • drowsiness
  • taste disorders
  • blurred vision
  • bronchospasm
  • abdominal pain
  • constipation
  • diarrhea
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  • abdominal bloating
  • nausea
  • vomiting
  • dry mouth
  • stomatitis
  • increased liver enzymes
  • hepatitis
  • dermatitis
  • itching
  • rash
  • hair loss
  • photosensitivity
  • fractures
  • arthralgia
  • myalgia
  • muscle weakness
  • allergic reactions
  • etc.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. Avoid storage in extremely hot or cold places, and it is recommended to keep it at room temperature between 1°C and 30°C.

Appearance and packaging

Appearance

Pink round film-coated tablet

Package unit

28 tablets/PTP [28 tablets (14 tablets/Alu-Alu X2)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.