Atorcell S Tablets 20 mg (Atorvastatin Calcium Hydrate)

Adult dosage

In treating hyperlipidemia, the recommended starting dose is 10 mg once daily. For patients requiring a greater reduction in LDL cholesterol levels, treatment can begin with 20 mg or 40 mg once daily. The dosage range is administered from 10 mg to 80 mg once daily. The initial and maintenance dosages should be individualized considering treatment goals and response, with lipid levels analyzed for dose adjustments within 2 to 4 weeks. The goal of treatment is to lower LDL cholesterol levels, so it is recommended to use LDL cholesterol levels to evaluate treatment initiation and response. However, if LDL cholesterol levels cannot be used, total cholesterol levels should be monitored to evaluate treatment response. For patients with homozygous familial hypercholesterolemia, the administration dose ranges from 10 mg to 80 mg once daily, either alongside other lipid-lowering therapies (e.g., LDL apheresis) or when such therapies are not possible.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10–17), the recommended starting dose is 10 mg once daily, and the recommended maximum dose is 20 mg once daily. The dosage should be adjusted appropriately according to treatment goals, with adjustments every 4 weeks.

This medication may present symptoms of muscle abnormalities, so if there is severe muscle pain or weakness or if creatine kinase levels rise significantly, use should be discontinued immediately. Patients at higher risk for severe myopathy or rhabdomyolysis should temporarily discontinue or stop using this medication. This drug should not be used in women who are pregnant or have specific diseases, children under 10 years old, and patients with certain liver diseases. Patients with alcohol dependence or impaired liver function should use this drug cautiously, and it is advised to check muscle enzyme levels before treatment in patients at risk of myopathy. If symptoms such as fatigue, muscle pain, or fever appear during the use of this medication, consult a doctor promptly. Also, as this drug can affect liver function, regular liver function tests are necessary, and if symptoms of hepatitis or jaundice appear, its use should be discontinued. Women of childbearing age should use appropriate contraceptive methods during treatment and should stop taking it if pregnancy occurs. This drug may interact with other medications, particularly specific antibiotics, antifungals, HIV treatments, and grapefruit juice, so caution is advised when used concomitantly. Elderly patients or those with reduced renal function are at increased risk for myopathy and should take extra precautions when using this drug. There is no specific antidote for overdose, thus treatment should be symptomatic, checking liver function and muscle enzyme tests to monitor the condition. Keep this medication out of the reach of children and store it safely in its original container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, pain in oral or ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough + fever, jaundice (yellowing of skin or eyes), extreme fatigue all over the body, sudden and severe headaches, lightning-type headaches, seizures, confusion of consciousness, visual disturbances, paralysis, urination

Mild side effects

• Weakness
• lethargy
• chest pain
• peripheral edema
• fatigue
• fever
• rhinitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is best to maintain storage temperatures between 1°C and 30°C.

Appearance

White round film-coated tablet

Package unit

100 tablets/bottle, 30 tablets/bottle