Entipozine 5/160 mg

Adult dose

The recommended dosage for adults is one tablet once daily, to be taken with water regardless of meals. It is advised to take it at the same time every day (e.g., in the morning). For patients whose blood pressure is not adequately controlled by amlodipine or valsartan monotherapy, dosages of 5/80 mg, 5/160 mg, or 10/160 mg can be administered. For patients with mild to moderate renal impairment, dosage adjustment is not necessary, however, for severe cases...

Child dose

The safety and efficacy of this medication in pediatric patients under 18 years of age have not been established, therefore its use is not recommended.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy; thus, it should not be taken by women who are pregnant or may become pregnant. Additionally, it should not be used by patients with known allergies to its components, severe kidney or liver disease, or certain heart conditions. Patients with sodium or fluid depletion may experience hypotension, so their condition should be carefully monitored before and during use, including blood pressure monitoring. Patients with hyperkalemia who take this medication alongside drugs that can raise potassium levels should have their potassium levels frequently checked. Patients with renal artery stenosis or those who have recently undergone kidney transplantation should closely monitor kidney function while taking this medication. If symptoms of angioedema occur, the medication should be discontinued immediately, and patients recovering from heart failure or myocardial infarction should use caution, closely monitoring kidney function and symptoms. Dizziness or fatigue may occur during operation of vehicles or machinery, so caution is required. This medication may impact kidney function or electrolyte balance when used in combination with other antihypertensive drugs, and regular check-ups should be conducted per the physician's instructions. Moreover, patients with compromised liver function may require dosage adjustments, and overdose may lead to hypotension or cardiac issues requiring immediate emergency treatment. The safety and efficacy of this medication in children under 18 years old have not been adequately established, hence its use is not recommended. Finally, nursing mothers are advised to avoid taking this medication.

Serious side effects

Hives, severe swelling (edema), angioedema, chest tightness, difficulty breathing, angioedema, cold sweat, pallor, severe allergic reaction, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, breathing difficulties accompanied by cough and fever, jaundice (yellowing of skin or eyes), profound lethargy, liver abnormalities (jaundice)

Mild side effects

• Headache
• dizziness
• drowsiness
• paresthesia
• vertigo
• tinnitus
• tachycardia
• palpitations
• syncope
• orthostatic hypotension

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is recommended to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature to preserve the drug's effectiveness.

Appearance

Dark yellow oval film-coated tablet

Package unit

28 tablets (14 tablets/PTP packaging X2)