Sebikan Tablet 5/20 mg

Adult dose

This medication is administered as one tablet once daily, regardless of meals, and it is recommended to take it at the same time each day (e.g., in the morning). The recommended dosing is as follows: - 5/20 mg: Administered to patients whose blood pressure is not adequately controlled by amlodipine 5 mg or olmesartan medoxomil 20 mg monotherapy. - 10/20 mg: Administered to patients not adequately controlled by olmesartan medoxomil 20 mg.

Child dose

Safety and efficacy in pediatric patients under 18 years have not been established.

This medication can cause serious harm to the fetus and newborn if taken during pregnancy, particularly in the second and third trimesters, so it should be discontinued immediately if pregnancy is confirmed. Patients with allergies to this drug's active ingredients or similar substances, pregnant or nursing women, individuals with severe liver dysfunction, patients with severe aortic stenosis, biliary obstruction, renal dialysis patients, patients in shock, and certain diabetic patients should not use this medication. Patients with hypotension due to lack of fluids or salt may experience initial hypotension, so their condition should be closely monitored, and appropriate measures should be taken if hypotension occurs. Also, sudden vasodilation can lead to hypotension, so special caution is required for patients with aortic stenosis. Patients with severe obstructive coronary artery disease should be cautious as the risk of angina or myocardial infarction may increase with this medication. Caution should be exercised in patients with heart failure, and patients with impaired renal function may experience changes in kidney function while taking this drug. In patients with liver dysfunction, metabolism of this drug may be slowed, necessitating dosage adjustments. While taking this medication, symptoms such as dizziness, headache, hypotension, edema, gastrointestinal symptoms may appear, so patients should consult their doctor if any unusual symptoms occur. This medication should be avoided during pregnancy due to risks to the fetus, and if breastfeeding, mothers should discontinue either breastfeeding or taking this medication as adverse reactions may occur in infants. It is not recommended for children under 18 years as safety and efficacy have not been established. Elderly patients may be more sensitive to this drug, so treatment should start at a low dose with dosage adjusted considering kidney and liver function. In cases of overdose, hypotension and decreased cardiac function may occur, necessitating immediate medical attention and continuous monitoring of blood pressure and cardiac status. This medication should be stored in a cool, dry place, avoiding moisture and heat, and kept out of reach of children; transferring to other containers should be avoided. Before starting this medication, patients must consult with a doctor or pharmacist regarding potential interactions with other medications they are currently taking.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, severe allergic reactions, severe skin reactions, yellowing of the skin or eyes (jaundice), liver dysfunction (jaundice), acute renal failure, severe edema associated with increased blood pressure, serious neurological symptoms (worsening of cerebrovascular accident), angioedema, increased creatinine levels in the blood, hematuria, toxic epidermal necrolysis, autoimmune hepatitis, leukopenia, thrombocytopenia, respiratory distress, asthma attacks, cough.

Mild side effects

• Dizziness
• headache
• drowsiness
• decreased libido
• orthostatic hypotension
• decreased potassium levels
• increased creatinine levels
• increased uric acid levels
• increased gamma-glutamyl transferase
• fatigue

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. Maintaining the storage temperature between 1 degree and 30 degrees Celsius is important. Doing so will help preserve the medication's effectiveness and prevent deterioration.

Appearance

White round film-coated tablets

Package unit

28 tablets/PTP [(14 tablets/PTP x 2)]