Medication info
RabeM 20 mg Tablets (Rabeprazole Sodium)

RabeM 20 mg Tablets (Rabeprazole Sodium)

Prescription medicationTablet경구
Ingredient · strength
Rabeprazole Sodium›20mg / 1 tablet
Manufacturer / importer
(주)마더스제약
Appearance
Light yellow round enteric-coated tablet
Packaging
28 tablets (14 tablets/Alu Alu pack x 2)
Approval status
Active

MFDS item code 201907783 · Approved 2019.11.07 · Insurance code 622804180

Summary

Main use
Treatment of gastric ulcer and duodenal ulcer, relief of symptoms of gastroesophageal reflux disease, etc. improvement of gastrointestinal diseases
Who takes it
Adults
Adult dose
Gastric ulcer, duodenal ulcer: generally, 10 mg is administered orally once daily, and 20 mg may be administered once daily depending on symptoms. Gastric ulcers are treated for up to 8 weeks, and duodenal ulcers for up to 6 weeks. Erosive or ulcerative gastroesophageal reflux disease: administer 10 mg or 20 mg once daily for 4 to 8 weeks, and if untreated after 8 weeks, additional treatment for 8 weeks may include 10 mg or 20 mg given twice daily (20 mg twice daily).

Ingredients

Manufacturer
(주)마더스제약

Efficacy & effects

Treatment of gastric ulcer and duodenal ulcer, relief of symptoms of gastroesophageal reflux disease, etc. improvement of gastrointestinal diseases

  • Gastric ulcer
  • duodenal ulcer
  • erosive gastroesophageal reflux disease
  • ulcerative gastroesophageal reflux disease
  • symptoms of gastroesophageal reflux disease
  • gastrointestinal ulcer
  • Zollinger-Ellison syndrome
View approved original text

This medication is effective for the treatment of gastric ulcers and duodenal ulcers and helps relieve the symptoms of erosive or ulcerative gastroesophageal reflux disease. It is also used for long-term maintenance therapy for gastroesophageal reflux disease to help prevent recurrence. In patients with gastrointestinal ulcers infected with Helicobacter pylori, it is used in combination with antibiotics to enhance treatment effectiveness. It is also used for conditions associated with excessive gastric acid secretion, such as Zollinger-Ellison syndrome. This medication is used to improve and treat symptoms of gastrointestinal diseases.

How to take

Adult dose

Gastric ulcer, duodenal ulcer: generally, 10 mg is administered orally once daily, and 20 mg may be administered once daily depending on symptoms. Gastric ulcers are treated for up to 8 weeks, and duodenal ulcers for up to 6 weeks. Erosive or ulcerative gastroesophageal reflux disease: administer 10 mg or 20 mg once daily for 4 to 8 weeks, and if untreated after 8 weeks, additional treatment for 8 weeks may include 10 mg or 20 mg given twice daily (20 mg twice daily).

Precautions

This medication should not be used in patients who are allergic to specific components or who have previously shown hypersensitivity reactions to this drug or similar drugs. Moreover, it should not be taken by patients currently taking certain antibiotics or other medications, nor by women who are pregnant or breastfeeding. Patients with poor liver function, elderly patients, or individuals with a history of drug allergies should use this medication with additional caution. While taking this medication, a variety of side effects may occur, including skin rash, itching, blood abnormalities, liver function abnormalities, cardiovascular issues, gastrointestinal symptoms, neurological issues, respiratory problems, muscle pain, skin abnormalities, vision or hearing issues, and urinary system abnormalities; if any symptoms arise, consult a doctor immediately. Additionally, regular blood tests and liver function tests are necessary during long-term use, and caution should be exercised as there may be an increased risk of fractures associated with osteoporosis. This medication suppresses gastric acid secretion and may slightly increase the risk of bacterial infections in the stomach; therefore, if symptoms such as diarrhea persist, inform the medical staff immediately. Caution is required when driving or operating machinery as drowsiness may occur. There may be interactions with other medications, so if you are taking any other drugs, you must inform the medical staff, especially as it should not be taken together with certain antivirals or antibiotics. It is safest not to use this medication during pregnancy or breastfeeding. Do not chew or crush this medication; swallow it whole as a tablet. Keep it out of the reach of children and do not transfer it to another container. Long-term use may cause impaired absorption of vitamin B12, so caution is necessary, and if any abnormal symptoms appear on the skin or joints, consult the medical staff immediately. In case of overdose, there is no specific antidote, so it is important to receive treatment based on symptoms.

Side effects and when to seek care immediately

Serious side effects

  • Hives
  • severe swelling (edema)
  • chest tightness
  • difficulty breathing
  • skin peeling
  • pain in oral/ocular mucosa
  • severe allergic reaction
  • severe skin abnormal reaction
  • respiratory issues
  • jaundice (yellowing of skin or eyes)
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  • severe lethargy
  • liver abnormalities (jaundice)
  • sudden and severe headache
  • thunderclap headache
  • seizures
  • confusion
  • visual disturbances
  • paralysis
  • serious neurological symptoms
  • significantly reduced urine output

Mild side effects

  • Rash
  • itching
  • reduced red blood cells
  • reduced white blood cells
  • increased white blood cells
  • increased eosinophils
  • increased neutrophils
  • reduced lymphocytes
  • anemia
  • petechiae
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  • lymphadenopathy
  • hypopigmented anemia
  • pancytopenia
  • agranulocytosis
  • reduced platelets
  • hemolytic anemia
  • ALT increase
  • AST increase
  • ALP increase
  • -GTP increase
  • LDH increase
  • total bilirubin increase
  • hypertension
  • myocardial infarction
  • abnormal ECG
  • migraine
  • syncope
  • angina
  • heart block
  • palpitations

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be susceptible to air or moisture, so it must be stored in a tightly sealed container. The storage temperature should be kept at room temperature between 1 to 30 degrees Celsius. This way, the effectiveness of the medication can be maintained for a long time.

Appearance and packaging

Appearance

Light yellow round enteric-coated tablet

Package unit

28 tablets (14 tablets/Alu Alu pack x 2)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.