Medication info

Sevican Plus Tablet 5/40/12.5 milligrams

Prescription medicationTablet경구Expired
Ingredient · strength
Olmesartan Medoxomil›40mg / 1 tabletAmlodipine Besylate›6.944mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
한국신텍스제약(주)
Appearance
Pale yellow round film-coated tablet
Packaging
30 tablets/box [10 tablets/Alu-Alu X 3]
Approval status
Expired

MFDS item code 201907669 · Approved 2019.11.01

This product's status changed to Expired on 2024.11.01. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Improvement in blood pressure control for essential hypertension
Who takes it
Adults · Children
Adult dose
This medication is taken once daily, one tablet with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). The recommended dosage is as follows: - 5/20/12.5mg: For patients with blood pressure that is not adequately controlled with Amlodipine/Olmesartan Medoxomil 5/20mg combination therapy. - 5/40/12.5mg: For patients with blood pressure that is not adequately controlled with Amlodipine/Olmesartan Medoxomil 5/40mg.
Child dose
The safety and efficacy of this medication have not been established in pediatric patients under 18 years of age, so its use is not recommended.

Ingredients

Manufacturer
한국신텍스제약(주)

Efficacy & effects

Improvement in blood pressure control for essential hypertension

  • Essential Hypertension
View approved original text

This medication is used in essential hypertension patients whose blood pressure is not adequately controlled with Olmesartan Medoxomil and Amlodipine combination therapy. The two ingredients work together to dilate blood vessels and lower blood pressure, effectively controlling hypertension. It helps to reduce the risk of cardiovascular diseases, ensuring effective blood pressure control for safe treatment.

How to take

Adult dose

This medication is taken once daily, one tablet with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). The recommended dosage is as follows: - 5/20/12.5mg: For patients with blood pressure that is not adequately controlled with Amlodipine/Olmesartan Medoxomil 5/20mg combination therapy. - 5/40/12.5mg: For patients with blood pressure that is not adequately controlled with Amlodipine/Olmesartan Medoxomil 5/40mg.

Child dose

The safety and efficacy of this medication have not been established in pediatric patients under 18 years of age, so its use is not recommended.

Precautions

This medication may cause serious harm to the fetus and newborn in the second and third trimesters of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. It should not be used in patients who have allergies to this drug or its components, severe renal or hepatic impairment, severe hypotension, or unstable heart failure after acute myocardial infarction. In patients with reduced blood volume or electrolyte imbalances, hypotension may occur, so their condition should be closely monitored before administration, and careful observation is necessary during treatment. This medication may affect renal function, so patients with renal impairment should have regular blood tests to monitor renal function and electrolyte levels. Patients with hepatic impairment or liver cirrhosis and patients with heart valve diseases require special caution when using this medication. While this medication is effective for hypertension treatment, it may cause very low blood pressure or symptoms such as dizziness or drowsiness, so caution is necessary when driving or operating machinery. During treatment, skin may become sensitive to sunlight, so it is advisable to avoid sun exposure and to use sunscreen. This medication can interact with other blood pressure medications, certain diuretics, lithium, and some analgesics, so it is essential to inform your doctor or pharmacist of any other medications being taken. Pregnant or breastfeeding women are advised not to take this medication, and if breastfeeding, it is safer to stop breastfeeding or discontinue the use of this drug. The safety and efficacy of this medication have not been established in children under 18 years of age, so it is recommended not to use it in this population. In case of overdose, symptoms such as hypotension, palpitations, and dizziness may occur, and immediate medical attention is required.

Side effects and when to seek care immediately

Serious side effects

Urticaria, angioedema, severe edema, hypertension, angina pectoris, myocardial infarction, arrhythmia, vasculitis (including necrotizing vasculitis), thrombosis, embolism, dyspnea, severe difficulty in breathing, acute respiratory distress syndrome (ARDS), pulmonary edema, jaundice (liver impairment), acute renal failure, hepatitis, cholestatic jaundice, autoimmune hepatitis, Stevens-Johnson syndrome, severe allergic reactions, serious skin reactions, severe neurological symptoms

Mild side effects

  • Peripheral edema
  • headache
  • dizziness
  • upper respiratory infection
  • nasopharyngitis
  • urinary tract infection
  • sialadenitis
  • leukopenia
  • thrombocytopenia
  • bone marrow suppression
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  • neutropenia/agranulocytosis
  • hemolytic anemia
  • aplastic anemia
  • drug hypersensitivity reaction
  • hyperkalemia
  • hypokalemia
  • anorexia
  • diabetes
  • hypercalcemia
  • hyperglycemia
  • hypomagnesemia
  • hyponatremia
  • hypochloremia
  • hypertriglyceridemia
  • hypercholesterolemia
  • hyperuricemia
  • hypochloremic metabolic alkalosis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture, and it should be kept at room temperature between 1 and 30 degrees Celsius. Proper storage will maintain the efficacy of the medication and prevent deterioration.

Appearance and packaging

Appearance

Pale yellow round film-coated tablet

Package unit

30 tablets/box [10 tablets/Alu-Alu X 3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.