Medication info
Boryeong Rasagiline Tablet 0.5 mg (Rasagiline Mesylate)

Boryeong Rasagiline Tablet 0.5 mg (Rasagiline Mesylate)

Prescription medicationTabletOral
Ingredient · strength
Rasagiline Mesylate›0.78mg / 1 tablet
Manufacturer / importer
Boryeong Co., Ltd.
Appearance
White round tablet
Packaging
30 tablets/box [10 tablets/PTP*3]
Approval status
Active

MFDS item code 201907626 · Approved 2019.10.31

Summary

Main use
Treatment of idiopathic Parkinson's disease
Who takes it
Adults
Adult dose
This medicine is administered orally once daily to adults as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If it is well tolerated and an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Ingredients

Manufacturer
Boryeong Co., Ltd.

Efficacy & effects

Treatment of idiopathic Parkinson's disease

  • Idiopathic Parkinson's disease
  • motor fluctuations
View approved original text

This medicine is used to treat idiopathic Parkinson's disease. Initially, it is used either as monotherapy or in conjunction with dopamine agonists to improve symptoms. It can also be used as adjunctive therapy for patients experiencing motor fluctuations, particularly the wearing-off phenomenon occurring after taking levodopa. This helps to maintain more stable motor function in patients with Parkinson's disease. This medication plays an important role in the treatment of Parkinson's disease.

How to take

Adult dose

This medicine is administered orally once daily to adults as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If it is well tolerated and an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Precautions

This drug should not be used in patients who are allergic to specific ingredients. It should be avoided when taken with other MAO inhibitors or certain analgesics and sedatives, as serious side effects may occur. It is safe to avoid administration in patients with moderate or severe liver function impairment. During the course of treatment, side effects such as cold, headache, dizziness, nausea, and skin rash may occur; if symptoms persist or worsen, consultation with a physician is necessary. Patients with Parkinson's disease may exhibit psychiatric symptoms such as hallucinations or confusion, so caution is required. There may be sudden increases in blood pressure, especially if foods high in tyramine are consumed excessively. While taking this medication, obsessive behaviors or impulse control disorders may arise, so patients and caregivers should carefully observe for such behavioral changes. Drowsiness or sudden sleep may occur during driving or operating machinery; if symptoms appear, the activity should be stopped immediately. Women who are pregnant or breastfeeding should take caution when using this medication, and it is advisable to consult a specialist if possible. In cases of overdose, severe hypertension or neurological symptoms may occur, so it is important to adhere to the prescribed dosage and inform a healthcare professional immediately if experiencing any abnormal symptoms. This medicine should be kept out of reach of children to ensure safety, and it is suggested to store it at a temperature between 1 to 25 degrees Celsius.

Side effects

  • Influenza
  • skin cancer
  • leukopenia
  • allergy
  • decreased appetite
  • depression
  • hallucinations
  • headache
  • cerebrovascular accident
  • conjunctivitis
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  • dizziness
  • angina
  • myocardial infarction
  • rhinitis
  • bloating
  • dermatitis
  • vesicular rash
  • musculoskeletal pain
  • neck pain
  • arthritis
  • urinary urgency
  • fever
  • fatigue
  • peripheral edema
  • falls
  • arthralgia
  • cough
  • insomnia
  • upper respiratory infection
  • nausea
  • constipation
  • vomiting
  • dry mouth
  • diarrhea
  • abdominal pain
  • indigestion
  • hernia
  • infection
  • gingivitis
  • accidental injury
  • weight loss
  • tendinitis
  • movement disorder
  • drowsiness
  • sensory disturbance
  • ataxia
  • muscle tone abnormality
  • myasthenia
  • appetite loss
  • abnormal dreams
  • respiratory distress
  • rash
  • hyperhidrosis
  • orthostatic hypotension
  • petechiae
  • hemorrhage
  • melanoma
  • confusion
  • carpal tunnel syndrome
  • balance disorder
  • hypertension
  • pathological gambling
  • increased libido
  • hypersexuality
  • compulsive buying
  • binge eating
  • compulsive eating
  • hypotension
  • excessive drowsiness
  • acute renal failure
  • vertebral fracture
  • rib fracture
  • tendon injury
  • pelvic fracture
  • leg fracture
  • upper limb fracture
  • back pain
  • knee arthroplasty
  • intervertebral disc herniation
  • hypoglycemia
  • weight loss
  • dysuria
  • malignant hyperthermia
  • systemic weakness
  • pulmonary tuberculosis
  • hallucinations
  • semi-coma
  • gait disturbance
  • ocular movement seizures
  • facial paralysis
  • spinal canal stenosis
  • worsening of Parkinson's disease
  • subdural hemorrhage
  • pneumonia
  • myalgia
  • osteoporosis
  • limb weakness
  • thirst
  • hematuria
  • frequent urination
  • vaginitis
  • conjunctival hyperemia
  • diplopia
  • visual impairment
  • skin thickening
  • palpitations
  • arrhythmia
  • gastrointestinal discomfort
  • gas reflux
  • excessive salivation
  • irritable bowel syndrome
  • fissured tongue
  • increased bowel movement frequency
  • unspecified bowel disease
  • esophagitis
  • hyperacidity
  • gastroesophageal reflux
  • gastric irritation
  • gastroenteritis
  • intestinal motility disorder
  • periodontitis
  • Helicobacter pylori gastritis
  • anemia
  • leg pain
  • chest pain
  • syncope
  • periorbital edema
  • facial flushing
  • pain
  • hallucination
  • sleep disorder
  • aggression
  • amnesia
  • memory impairment
  • lethargy
  • sleep talking
  • psychosexual disorder
  • paresthesia
  • tremor
  • freezing phenomenon
  • limb tremors
  • myoclonus
  • leg cramps
  • polyuria
  • tremors
  • stuttering
  • vocal disorder
  • vocal cord paralysis
  • language disorder
  • localized inflammation
  • itching
  • urticaria
  • eyelid skin disease
  • boil
  • alopecia
  • contusion
  • abnormal sputum
  • increased sputum
  • cold
  • bronchitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medicine should be stored in a tightly sealed container to protect it from air and moisture in a cool place, maintaining a temperature between 1 and 25 degrees Celsius. This helps to prolong the efficacy of the medication.

Appearance and packaging

Appearance

White round tablet

Package unit

30 tablets/box [10 tablets/PTP*3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.