Thianin Tablet (Tianephtin Sodium)

Adult dose

○ Adults : Administer 12.5 mg of tianeptine sodium orally 3 times daily before meals. ○ In elderly patients aged 70 years or older or patients with renal impairment, limit the dose to twice daily. ○ Adjust the dose appropriately according to symptoms. ○ Abrupt discontinuation of treatment should be avoided. To reduce the risk of withdrawal reactions, gradually reduce the dose over 7 ~ 14 days. (See the ‘General Precautions’ section under Precautions for Use.)

This medication is used for the treatment of depression, but it may carry a risk of suicidal thoughts or self-harming behaviors, so the patient's condition should be closely monitored at the beginning of treatment. Special attention is needed for patients with a history of suicide attempts or suicidal ideation. It should not be used in children under 15 years of age and should not be taken in conjunction with certain drugs such as MAO inhibitors. Patients with rare genetic disorders such as fructose intolerance or glucose-galactose malabsorption should also avoid this medication. Various side effects such as loss of appetite, nightmares, insomnia, drowsiness, headache, palpitations, digestive disturbances may occur while taking this medication, so it is advisable to consult with a doctor if abnormalities arise. Prior to surgery, inform the anesthesiologist of this medication use, and it may be necessary to discontinue it 24-48 hours before surgery. It should not be taken with alcohol, and patients with a history of drug dependence should be careful to avoid overdose. Pregnant or nursing women should avoid this medication. In elderly patients, the drug's half-life may be prolonged, so it is safer to limit the dosage to twice a day. Do not suddenly stop the medication; the dosage should be gradually reduced under medical supervision to prevent withdrawal symptoms. Overdose may result in drowsiness or stupor, requiring immediate emergency treatment. This medication should be stored out of the reach of children and should not be transferred to another container.

• Loss of appetite
• hyponatremia
• nightmares
• drug abuse and dependence
• suicidal thoughts
• suicidal behavior
• confusion
• hallucinations
• insomnia
• drowsiness

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1°C and 30°C to preserve the drug's effectiveness and safety over time.

Appearance

White oval film-coated tablet

Package unit

Domestic use - 30 tablets/bottle, Domestic use - 300 tablets/bottle