Selcobix Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient. It may be taken with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or take 100 mg twice daily in divided doses. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg twice daily in divided doses. If no effect is observed after 6 weeks, a dose of up to 400 mg daily may be administered. If no effect is observed after 6 weeks of treatment with 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. Starting on the second day of treatment, the recommended dose as needed is 200 mg twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medicine may cause gastric bleeding if taken by individuals who consume a lot of alcohol daily; therefore, consultation with a doctor or pharmacist is essential. It may affect the cardiovascular system, increasing the risk of myocardial infarction or stroke, so it should only be used at the minimum effective dose and for the shortest duration possible. Immediate medical consultation is necessary if cardiovascular symptoms appear. For individuals with gastrointestinal issues or the elderly, the risk of gastric ulcer, bleeding, perforation, etc., is high, thus caution is required. If symptoms such as stomach pain, black stools, or vomiting blood occur, immediate medical attention should be sought. Patients who are allergic to this drug or have severely impaired liver or kidney function, or active gastric bleeding should not take this medication. Patients with weak liver or kidney function, asthma, heart failure, hypertension, or the elderly should use this drug cautiously, and regular monitoring may be necessary. This drug can have various side effects; therefore, it is crucial to notify healthcare professionals immediately if dizziness, drowsiness, skin rash, breathing difficulties, or other abnormal symptoms occur during use. As this drug has numerous interactions with other medications, it is important to inform healthcare providers of any other medications being taken, especially when used with blood pressure medications, anticoagulants, antidepressants, or diuretics. Women who are pregnant or may become pregnant and nursing mothers should not take this medication, and if pregnancy is confirmed while taking it, they should immediately stop use and consult a healthcare professional. Safety for children and adolescents has not been established, so it is advisable not to use this medication in this age group. The elderly may have impaired kidney, liver, or heart function; therefore, they should use the drug with additional caution, and dosage adjustments may be necessary. Long-term users of this medication should have regular blood tests and tests for liver and kidney function to check for abnormalities. In case of overdose, symptoms such as nausea, vomiting, drowsiness, and gastric bleeding may occur, necessitating immediate medical attention. This medication should be stored out of the reach of children, and care should be taken not to transfer it to another container as this could affect the quality.

Gastrointestinal bleeding, cardiovascular thrombotic events, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tracts, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, distention, gastric ulcer, dental disorders, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, dysgeusia, albuminuria, cystitis, hematuria, dysuria, frequency, kidney stones, incontinence, urinary tract infections, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular bleeding, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, menstrual disorders, chest pain, hallucinations, cerebral hemorrhage, aseptic meningitis, anosmia, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized fixed drug eruption, fixed drug eruption, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis, anaphylactic reaction, vasculitis, vesicular dermatitis, vasculitis, angioedema, thrombophlebitis, vasculitis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, epistaxis, thrombocytopenia, headache, leg cramps, tension, sensory impairment, migraine, neuralgia, neuropathy, paresthesia, ataxia, suicide, anosmia, ageusia, weakness, fluid retention, systemic edema, facial edema, fatigue, malaise, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, angioedema, insomnia, appetite loss, increased appetite, depression, neuropsychiatric reactions, drowsiness, fatal intracranial hemorrhage, confusion, hallucination, seizure' exacerbation, upper respiratory tract infections, herpes simplex, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infections, fungal infections, soft tissue infections, viral infections, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, tinnitus, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, increased sodium in blood, increased potassium in blood, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, appetite loss, increased LDH, hypoglycemia, hyponatremia, bursa, arthralgia, arthropathy, skeletal deformities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, fractures, tendon rupture, pain in the back, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, anemia, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, folliculitis, contact dermatitis, injection site reactions, skin nodules, dysgeusia, albuminuria, cystitis, hematuria, dysuria, frequency, kidney stones, incontinence, urinary tract infections, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular bleeding, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis

This medication should be stored in a sealed container to prevent air or moisture from entering, and it is advisable to keep it in a cool place between 15 to 30 degrees Celsius. This way, the effectiveness of the medication can be maintained for a longer time.

Appearance

An opaque white hard capsule filled with a white to pale yellow powder, marked with blue lines on the top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle